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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PURB All Species: 1.21
Human Site: S23 Identified Species: 2.67
UniProt: Q96QR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QR8 NP_150093.1 312 33241 S23 P C G F Q P A S R G G G E Q E
Chimpanzee Pan troglodytes XP_001136727 295 32969 A23 S G G G G G G A P G G L Q H E
Rhesus Macaque Macaca mulatta XP_001085613 304 33781 G32 G S G S G S G G G G G L Q H E
Dog Lupus familis XP_850017 341 36742 A58 T A S A E R G A S S R E D T E
Cat Felis silvestris
Mouse Mus musculus O35295 324 33883 G35 R G G G G G G G G P G G E Q E
Rat Rattus norvegicus Q68A21 315 33399 G26 Q P A P R G G G G P G G E Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426295 336 38538 L37 P L T P A H L L R G G C H G D
Frog Xenopus laevis Q8AVS4 328 34968 H23 G P S G F S Q H M S R E Q E T
Zebra Danio Brachydanio rerio Q6PHK6 297 32588 E23 G L Q H F Q R E Q E T Q E L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784262 259 29404
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKZ1 296 32182 S33 G S D V E L V S K T L Q V E H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.5 70.5 82.1 N.A. 94.4 97.1 N.A. N.A. 51.4 81.7 83 N.A. N.A. N.A. N.A. 45.8
Protein Similarity: 100 79.1 79.1 83.5 N.A. 95.3 97.4 N.A. N.A. 64.2 86.2 87.8 N.A. N.A. N.A. N.A. 62.1
P-Site Identity: 100 26.6 26.6 6.6 N.A. 40 33.3 N.A. N.A. 26.6 0 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 40 33.3 26.6 N.A. 40 40 N.A. N.A. 33.3 13.3 13.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 10 0 10 19 0 0 0 0 0 0 10 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 10 % D
% Glu: 0 0 0 0 19 0 0 10 0 10 0 19 37 19 55 % E
% Phe: 0 0 0 10 19 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 37 19 37 28 28 28 46 28 28 37 55 28 0 10 0 % G
% His: 0 0 0 10 0 10 0 10 0 0 0 0 10 19 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 19 0 0 0 10 10 10 0 0 10 19 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 19 0 19 0 10 0 0 10 19 0 0 0 0 0 % P
% Gln: 10 0 10 0 10 10 10 0 10 0 0 19 28 28 0 % Q
% Arg: 10 0 0 0 10 10 10 0 19 0 19 0 0 0 0 % R
% Ser: 10 19 19 10 0 19 0 19 10 19 0 0 0 0 0 % S
% Thr: 10 0 10 0 0 0 0 0 0 10 10 0 0 10 10 % T
% Val: 0 0 0 10 0 0 10 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _