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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PURB All Species: 10.61
Human Site: S298 Identified Species: 23.33
UniProt: Q96QR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QR8 NP_150093.1 312 33241 S298 Y E R R G G G S G G G E E S E
Chimpanzee Pan troglodytes XP_001136727 295 32969 A280 Q Q Q Q E E T A A A T L L L Q
Rhesus Macaque Macaca mulatta XP_001085613 304 33781 A289 Q Q Q Q E E T A A A T L L L Q
Dog Lupus familis XP_850017 341 36742 R327 Q R D K L Y E R R G G D E S E
Cat Felis silvestris
Mouse Mus musculus O35295 324 33883 S310 Y E R R G G G S G G G D E S E
Rat Rattus norvegicus Q68A21 315 33399 S301 Y E R R G G G S G G G D E S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426295 336 38538 D323 S H K E K R M D V R G D S G E
Frog Xenopus laevis Q8AVS4 328 34968 E304 Y D R R G P G E R G G S L G P
Zebra Danio Brachydanio rerio Q6PHK6 297 32588 Y283 E R H R D K M Y E R R E E S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784262 259 29404 I246 Y V D R M K E I R A G E G G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKZ1 296 32182 M283 T K D K I E G M T G A N V R T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.5 70.5 82.1 N.A. 94.4 97.1 N.A. N.A. 51.4 81.7 83 N.A. N.A. N.A. N.A. 45.8
Protein Similarity: 100 79.1 79.1 83.5 N.A. 95.3 97.4 N.A. N.A. 64.2 86.2 87.8 N.A. N.A. N.A. N.A. 62.1
P-Site Identity: 100 0 0 33.3 N.A. 93.3 93.3 N.A. N.A. 13.3 46.6 33.3 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 33.3 33.3 46.6 N.A. 100 100 N.A. N.A. 26.6 53.3 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 19 19 28 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 28 0 10 0 0 10 0 0 0 37 0 0 0 % D
% Glu: 10 28 0 10 19 28 19 10 10 0 0 28 46 0 55 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 37 28 46 0 28 55 64 0 10 28 0 % G
% His: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 10 10 19 10 19 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 0 19 28 19 0 % L
% Met: 0 0 0 0 10 0 19 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % P
% Gln: 28 19 19 19 0 0 0 0 0 0 0 0 0 0 19 % Q
% Arg: 0 19 37 55 0 10 0 10 28 19 10 0 0 10 0 % R
% Ser: 10 0 0 0 0 0 0 28 0 0 0 10 10 46 0 % S
% Thr: 10 0 0 0 0 0 19 0 10 0 19 0 0 0 10 % T
% Val: 0 10 0 0 0 0 0 0 10 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 46 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _