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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACCS All Species: 20.61
Human Site: S114 Identified Species: 41.21
UniProt: Q96QU6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QU6 NP_001120691.1 501 57324 S114 K L C F D L L S W R L S Q R D
Chimpanzee Pan troglodytes XP_508382 689 77359 S302 K L C F D L L S W R L S Q S D
Rhesus Macaque Macaca mulatta XP_001113725 501 56887 S114 K L C F D L L S W R L S Q S D
Dog Lupus familis XP_854150 603 67679 S113 K L C F D L L S R R L S Q S D
Cat Felis silvestris
Mouse Mus musculus A2AIG8 502 56860 S115 K L C F D L L S W R L T Q G D
Rat Rattus norvegicus Q58FK9 454 51026 A89 Q E E L S K A A F I D N L N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421096 872 99459 S435 K L C F D L M S K R L T Q T D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001014345 556 63104 L124 V M N G C G S L F S A L A A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781499 294 33099
Poplar Tree Populus trichocarpa XP_002320015 468 52759 R103 V E F M A E I R G N K V T F D
Maize Zea mays NP_001146401 486 53748 G110 K F M G Q V R G G K V T F D P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9T065 469 53352 G104 D F M S E N R G N R V S F N P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.9 95.6 70.1 N.A. 82.8 20.9 N.A. N.A. 39.6 N.A. 48.5 N.A. N.A. N.A. N.A. 23.5
Protein Similarity: 100 72.1 97.5 74.9 N.A. 89.4 38.5 N.A. N.A. 48.3 N.A. 62.7 N.A. N.A. N.A. N.A. 37.3
P-Site Identity: 100 93.3 93.3 86.6 N.A. 86.6 0 N.A. N.A. 73.3 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 93.3 26.6 N.A. N.A. 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: 28.9 29.3 N.A. 29.3 N.A. N.A.
Protein Similarity: 45.9 46.1 N.A. 45.1 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 13.3 33.3 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 9 9 0 0 9 0 9 9 0 % A
% Cys: 0 0 50 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 50 0 0 0 0 0 9 0 0 9 59 % D
% Glu: 0 17 9 0 9 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 17 9 50 0 0 0 0 17 0 0 0 17 9 0 % F
% Gly: 0 0 0 17 0 9 0 17 17 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % I
% Lys: 59 0 0 0 0 9 0 0 9 9 9 0 0 0 0 % K
% Leu: 0 50 0 9 0 50 42 9 0 0 50 9 9 0 0 % L
% Met: 0 9 17 9 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 9 0 0 9 9 0 9 0 17 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % P
% Gln: 9 0 0 0 9 0 0 0 0 0 0 0 50 0 9 % Q
% Arg: 0 0 0 0 0 0 17 9 9 59 0 0 0 9 0 % R
% Ser: 0 0 0 9 9 0 9 50 0 9 0 42 0 25 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 25 9 9 9 % T
% Val: 17 0 0 0 0 9 0 0 0 0 17 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _