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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACCS All Species: 21.82
Human Site: S265 Identified Species: 43.64
UniProt: Q96QU6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QU6 NP_001120691.1 501 57324 S265 N P L G D V Y S P E E L Q E Y
Chimpanzee Pan troglodytes XP_508382 689 77359 S453 N P L G D V Y S P E E L Q E Y
Rhesus Macaque Macaca mulatta XP_001113725 501 56887 S265 N P L G D I Y S P E E L Q E Y
Dog Lupus familis XP_854150 603 67679 S264 N P L G D I Y S P G E L R D Y
Cat Felis silvestris
Mouse Mus musculus A2AIG8 502 56860 S266 N P L G D V Y S P E E L Q D F
Rat Rattus norvegicus Q58FK9 454 51026 L235 E L Q V I A D L C I K H D T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421096 872 99459 S586 N P L G D I Y S L S E L R D Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001014345 556 63104 Q295 S E N K D L V Q A L D Q L G C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781499 294 33099 L75 E G H N V R A L L L V N P V N
Poplar Tree Populus trichocarpa XP_002320015 468 52759 V249 G F V S V M E V L K D M K C E
Maize Zea mays NP_001146401 486 53748 E257 V S I A E V I E R G D A P G C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9T065 469 53352 L250 F I S V M E V L K D R K L E N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.9 95.6 70.1 N.A. 82.8 20.9 N.A. N.A. 39.6 N.A. 48.5 N.A. N.A. N.A. N.A. 23.5
Protein Similarity: 100 72.1 97.5 74.9 N.A. 89.4 38.5 N.A. N.A. 48.3 N.A. 62.7 N.A. N.A. N.A. N.A. 37.3
P-Site Identity: 100 100 93.3 73.3 N.A. 86.6 0 N.A. N.A. 66.6 N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 6.6 N.A. N.A. 86.6 N.A. 26.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: 28.9 29.3 N.A. 29.3 N.A. N.A.
Protein Similarity: 45.9 46.1 N.A. 45.1 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 26.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 9 0 9 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 17 % C
% Asp: 0 0 0 0 59 0 9 0 0 9 25 0 9 25 0 % D
% Glu: 17 9 0 0 9 9 9 9 0 34 50 0 0 34 9 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 9 9 0 50 0 0 0 0 0 17 0 0 0 17 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 9 9 0 9 25 9 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 9 9 9 9 9 0 0 % K
% Leu: 0 9 50 0 0 9 0 25 25 17 0 50 17 0 9 % L
% Met: 0 0 0 0 9 9 0 0 0 0 0 9 0 0 0 % M
% Asn: 50 0 9 9 0 0 0 0 0 0 0 9 0 0 17 % N
% Pro: 0 50 0 0 0 0 0 0 42 0 0 0 17 0 0 % P
% Gln: 0 0 9 0 0 0 0 9 0 0 0 9 34 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 9 0 9 0 17 0 0 % R
% Ser: 9 9 9 9 0 0 0 50 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % T
% Val: 9 0 9 17 17 34 17 9 0 0 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 42 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _