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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACCS All Species: 16.67
Human Site: S482 Identified Species: 33.33
UniProt: Q96QU6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QU6 NP_001120691.1 501 57324 S482 Q Q V L A G K S Q V A E D P R
Chimpanzee Pan troglodytes XP_508382 689 77359 S670 R Q V L A G K S Q V A E D P R
Rhesus Macaque Macaca mulatta XP_001113725 501 56887 S482 R Q V L A G K S Q V A E D P P
Dog Lupus familis XP_854150 603 67679 S481 R Q V L E G K S Q A A E A R S
Cat Felis silvestris
Mouse Mus musculus A2AIG8 502 56860 S483 R Q V L E G Q S Q V V E D A S
Rat Rattus norvegicus Q58FK9 454 51026 D436 R F C F I K K D S T L D A A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421096 872 99459 K811 Q E I L S E E K E Q P C Q S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001014345 556 63104 P533 D W L E K H R P E L A A G V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781499 294 33099 N276 P G A A F Y Y N E F G W I R L
Poplar Tree Populus trichocarpa XP_002320015 468 52759 L450 K N A R R K S L A K W V L R L
Maize Zea mays NP_001146401 486 53748 S465 R R G A T T A S H L A I S S P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9T065 469 53352 K451 L K N L R K M K V S N W V F R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.9 95.6 70.1 N.A. 82.8 20.9 N.A. N.A. 39.6 N.A. 48.5 N.A. N.A. N.A. N.A. 23.5
Protein Similarity: 100 72.1 97.5 74.9 N.A. 89.4 38.5 N.A. N.A. 48.3 N.A. 62.7 N.A. N.A. N.A. N.A. 37.3
P-Site Identity: 100 93.3 86.6 60 N.A. 60 6.6 N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 66.6 N.A. 73.3 20 N.A. N.A. 46.6 N.A. 33.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 28.9 29.3 N.A. 29.3 N.A. N.A.
Protein Similarity: 45.9 46.1 N.A. 45.1 N.A. N.A.
P-Site Identity: 0 13.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: 6.6 33.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 17 25 0 9 0 9 9 50 9 17 17 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 9 0 0 0 9 34 0 17 % D
% Glu: 0 9 0 9 17 9 9 0 25 0 0 42 0 0 9 % E
% Phe: 0 9 0 9 9 0 0 0 0 9 0 0 0 9 0 % F
% Gly: 0 9 9 0 0 42 0 0 0 0 9 0 9 0 0 % G
% His: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 0 0 0 0 0 9 9 0 0 % I
% Lys: 9 9 0 0 9 25 42 17 0 9 0 0 0 0 0 % K
% Leu: 9 0 9 59 0 0 0 9 0 17 9 0 9 0 17 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 9 0 0 0 0 9 0 0 9 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 9 0 0 9 0 0 25 17 % P
% Gln: 17 42 0 0 0 0 9 0 42 9 0 0 9 0 0 % Q
% Arg: 50 9 0 9 17 0 9 0 0 0 0 0 0 25 25 % R
% Ser: 0 0 0 0 9 0 9 50 9 9 0 0 9 17 17 % S
% Thr: 0 0 0 0 9 9 0 0 0 9 0 0 0 0 0 % T
% Val: 0 0 42 0 0 0 0 0 9 34 9 9 9 9 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 9 17 0 0 0 % W
% Tyr: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _