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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PANX3 All Species: 28.18
Human Site: T370 Identified Species: 77.5
UniProt: Q96QZ0 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QZ0 NP_443191.1 392 44683 T370 D T V V D F M T L L A G L E P
Chimpanzee Pan troglodytes XP_001138163 392 44593 T370 D T V V D F M T L L A G L E P
Rhesus Macaque Macaca mulatta XP_001109098 392 44719 T370 D T V V D F M T L L A G L E P
Dog Lupus familis XP_852341 392 44900 T370 D T V V D F M T L L A G L E P
Cat Felis silvestris
Mouse Mus musculus Q8CEG0 392 44910 T370 D T V V D F M T F V A G L E P
Rat Rattus norvegicus P60572 392 44959 T370 D T V V D F M T L L A G L E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513293 535 58984 T440 I L L T N L G T I K T D V V D
Chicken Gallus gallus XP_001231503 409 45992 T370 D T V V D F M T L L A G L E A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919861 444 50623 E371 V L T E E Q A E E M L E T A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.4 90 N.A. 88.7 91.5 N.A. 28 66.7 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 99.2 94.9 N.A. 93.3 95.6 N.A. 43.3 77.7 N.A. 67.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 100 N.A. 6.6 93.3 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 33.3 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 12 0 0 0 78 0 0 12 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 78 0 0 0 78 0 0 0 0 0 0 12 0 0 12 % D
% Glu: 0 0 0 12 12 0 0 12 12 0 0 12 0 78 12 % E
% Phe: 0 0 0 0 0 78 0 0 12 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 12 0 0 0 0 78 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % K
% Leu: 0 23 12 0 0 12 0 0 67 67 12 0 78 0 0 % L
% Met: 0 0 0 0 0 0 78 0 0 12 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 78 12 12 0 0 0 89 0 0 12 0 12 0 0 % T
% Val: 12 0 78 78 0 0 0 0 0 12 0 0 12 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _