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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NACC1 All Species: 18.48
Human Site: S140 Identified Species: 50.83
UniProt: Q96RE7 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RE7 NP_443108.1 527 57258 S140 L H A E E A P S S E P Q S P V
Chimpanzee Pan troglodytes XP_520360 586 62800 S140 A V I E D A G S E P Q S P C N
Rhesus Macaque Macaca mulatta XP_001116354 373 40194 Q26 C L N E Q R L Q G L Y C D V S
Dog Lupus familis XP_542034 517 55515 S140 L H A E E A P S S E P Q S P V
Cat Felis silvestris
Mouse Mus musculus Q7TSZ8 514 56518 S140 L H P E E A P S S E P Q S P V
Rat Rattus norvegicus O35260 514 56431 S140 L H P E E A P S S E P Q S P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510474 490 53738 S140 L H A E E T P S S E P Q S P V
Chicken Gallus gallus Q92010 448 51031 K101 Y T A K I S V K K E D V N L M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691216 635 67265 P144 L H T E E T P P S E P Q S P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.6 70.2 86.5 N.A. 88 88 N.A. 78.7 20.1 N.A. 59.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 60.2 70.2 89.1 N.A. 91 90.6 N.A. 82.1 37.7 N.A. 67.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 6.6 100 N.A. 93.3 93.3 N.A. 93.3 13.3 N.A. 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 13.3 100 N.A. 93.3 93.3 N.A. 93.3 40 N.A. 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 45 0 0 56 0 0 0 0 0 0 0 0 0 % A
% Cys: 12 0 0 0 0 0 0 0 0 0 0 12 0 12 0 % C
% Asp: 0 0 0 0 12 0 0 0 0 0 12 0 12 0 0 % D
% Glu: 0 0 0 89 67 0 0 0 12 78 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 12 0 12 0 0 0 0 0 0 % G
% His: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 0 0 12 12 0 0 0 0 0 0 % K
% Leu: 67 12 0 0 0 0 12 0 0 12 0 0 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 0 12 0 12 % N
% Pro: 0 0 23 0 0 0 67 12 0 12 67 0 12 67 0 % P
% Gln: 0 0 0 0 12 0 0 12 0 0 12 67 0 0 0 % Q
% Arg: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 12 0 67 67 0 0 12 67 0 12 % S
% Thr: 0 12 12 0 0 23 0 0 0 0 0 0 0 0 0 % T
% Val: 0 12 0 0 0 0 12 0 0 0 0 12 0 12 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _