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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR1H4
All Species:
13.64
Human Site:
Y77
Identified Species:
25
UniProt:
Q96RI1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RI1
NP_005114.1
486
55914
Y77
Q
I
S
S
S
S
Y
Y
S
N
L
G
F
Y
P
Chimpanzee
Pan troglodytes
XP_509299
482
55475
Y77
Q
I
S
S
S
S
Y
Y
S
N
L
G
F
Y
P
Rhesus Macaque
Macaca mulatta
XP_001090182
482
55476
Y77
Q
I
S
S
S
S
Y
Y
S
N
L
G
F
Y
P
Dog
Lupus familis
XP_866622
455
52340
R69
S
G
I
Y
E
L
R
R
M
P
A
E
T
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q60641
488
56018
Y77
Q
I
S
S
S
S
Y
Y
S
N
L
G
F
Y
P
Rat
Rattus norvegicus
Q62735
469
53916
Q71
S
N
L
G
F
Y
P
Q
Q
P
E
D
W
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506579
453
52254
R71
P
G
M
Y
E
L
R
R
I
P
S
D
N
I
C
Chicken
Gallus gallus
P22448
455
50690
L71
Q
S
T
S
S
E
E
L
V
P
S
P
P
S
P
Frog
Xenopus laevis
P18119
414
46688
V46
L
I
G
A
V
A
R
V
S
G
Y
I
P
S
Y
Zebra Danio
Brachydanio rerio
Q9PTN2
453
50848
C73
F
H
F
N
A
M
T
C
E
G
C
K
G
F
F
Tiger Blowfish
Takifugu rubipres
Q9W5Z3
447
49514
P73
S
P
P
S
P
P
P
P
P
R
V
Y
K
P
C
Fruit Fly
Dros. melanogaster
P34021
878
93835
N186
H
H
A
N
G
T
P
N
G
L
I
G
V
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123279
490
55735
I71
E
Q
S
S
P
Q
S
I
S
S
E
G
S
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.3
88.6
N.A.
92.2
86.8
N.A.
81.2
28.3
26.3
20.9
29.6
22.5
N.A.
N.A.
40.2
Protein Similarity:
100
99.1
98.5
91.3
N.A.
95.6
91.9
N.A.
86.8
46.2
44.4
40.5
47.3
34.4
N.A.
N.A.
57.9
P-Site Identity:
100
100
100
0
N.A.
100
6.6
N.A.
0
26.6
13.3
0
6.6
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
0
N.A.
100
13.3
N.A.
0
33.3
26.6
20
13.3
33.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
16
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% D
% Glu:
8
0
0
0
16
8
8
0
8
0
16
8
0
0
0
% E
% Phe:
8
0
8
0
8
0
0
0
0
0
0
0
31
8
8
% F
% Gly:
0
16
8
8
8
0
0
0
8
16
0
47
8
0
16
% G
% His:
8
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
39
8
0
0
0
0
8
8
0
8
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% K
% Leu:
8
0
8
0
0
16
0
8
0
8
31
0
0
0
0
% L
% Met:
0
0
8
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
16
0
0
0
8
0
31
0
0
8
0
0
% N
% Pro:
8
8
8
0
16
8
24
8
8
31
0
8
16
8
39
% P
% Gln:
39
8
0
0
0
8
0
8
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
24
16
0
8
0
0
0
0
0
% R
% Ser:
24
8
39
54
39
31
8
0
47
8
16
0
8
16
8
% S
% Thr:
0
0
8
0
0
8
8
0
0
0
0
0
8
8
0
% T
% Val:
0
0
0
0
8
0
0
8
8
0
8
0
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
16
0
8
31
31
0
0
8
8
0
39
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _