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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13A
All Species:
11.21
Human Site:
S2590
Identified Species:
27.41
UniProt:
Q96RL7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RL7
NP_001018047.1
3174
360276
S2590
E
Y
T
E
S
S
P
S
E
D
K
V
I
Q
L
Chimpanzee
Pan troglodytes
XP_001148547
3174
360353
S2590
E
Y
T
E
S
S
P
S
E
D
K
V
I
E
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533522
3194
361576
S2609
E
Y
T
E
S
S
P
S
E
D
K
V
I
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5H8C4
3166
359382
L2583
E
Y
T
E
A
S
P
L
E
D
K
V
V
E
L
Rat
Rattus norvegicus
NP_001094445
3167
360039
L2583
E
Y
T
E
S
S
P
L
E
D
K
V
V
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511611
3012
340425
Y2486
Y
T
K
Q
E
V
A
Y
I
G
I
T
S
S
D
Chicken
Gallus gallus
XP_001233000
3758
422392
T3155
L
C
K
T
A
F
Q
T
P
G
W
H
K
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001112365
3194
360237
V2607
D
Y
M
E
N
G
P
V
D
S
T
I
I
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610299
3321
374527
V2733
K
Y
L
V
H
K
S
V
N
D
V
Q
T
Y
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07878
3144
357831
S2566
T
S
S
V
S
V
N
S
S
V
T
D
G
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
84.1
N.A.
84.3
84.4
N.A.
61.5
36.9
N.A.
57.3
N.A.
30.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
90.6
N.A.
92.1
92.3
N.A.
76.6
54.5
N.A.
73.8
N.A.
52.2
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
73.3
80
N.A.
0
0
N.A.
33.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
13.3
N.A.
60
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
60
0
10
0
10
20
% D
% Glu:
50
0
0
60
10
0
0
0
50
0
0
0
0
40
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
20
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
10
10
40
0
0
% I
% Lys:
10
0
20
0
0
10
0
0
0
0
50
0
10
0
10
% K
% Leu:
10
0
10
0
0
0
0
20
0
0
0
0
0
10
60
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
60
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
50
50
10
40
10
10
0
0
10
10
0
% S
% Thr:
10
10
50
10
0
0
0
10
0
0
20
10
10
0
0
% T
% Val:
0
0
0
20
0
20
0
20
0
10
10
50
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
70
0
0
0
0
0
10
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _