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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GFM1 All Species: 15.45
Human Site: S345 Identified Species: 26.15
UniProt: Q96RP9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RP9 NP_079272.4 751 83471 S345 K T K I L M N S S R D N S H P
Chimpanzee Pan troglodytes XP_001154618 751 83449 S345 K T K I L M N S S R D N S H P
Rhesus Macaque Macaca mulatta XP_001094832 770 85971 S364 K T K I L M N S S R D N S H P
Dog Lupus familis XP_534320 771 85436 S365 Q N K I L M N S E R N S S H P
Cat Felis silvestris
Mouse Mus musculus Q8K0D5 751 83531 Q346 T K I L M N P Q R D D S H P F
Rat Rattus norvegicus Q07803 751 83439 K346 N K I L M N P K R D D S H P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233639 738 82390 A333 A K F L L N S A R D N S Q P F
Frog Xenopus laevis A5PKR8 748 83504 D343 S R I L M K S D R D S S Q P F
Zebra Danio Brachydanio rerio Q08BB1 745 82731 T340 S K I L M D S T R D D T Q P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM33 745 83491 R341 K V V L N P A R D G K D P F V
Honey Bee Apis mellifera XP_394825 744 84514 S345 I L L N S E R S N K H P F I G
Nematode Worm Caenorhab. elegans Q9XV52 750 83636 K343 K G I I L S P K R N N D K P F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C641 754 83160 P362 R V T L T G S P D G P L V A L
Baker's Yeast Sacchar. cerevisiae P25039 761 84555 V371 K V N L V P A V Q Q P F V G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.6 88.9 N.A. 90.4 90.4 N.A. N.A. 81.3 80.2 78 N.A. 65.1 61.9 55.2 N.A.
Protein Similarity: 100 100 96.4 93.9 N.A. 94.8 95.2 N.A. N.A. 90.5 89.7 89.8 N.A. 78.8 77.2 71.3 N.A.
P-Site Identity: 100 100 100 66.6 N.A. 6.6 6.6 N.A. N.A. 6.6 0 6.6 N.A. 6.6 6.6 20 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 26.6 26.6 N.A. N.A. 40 26.6 33.3 N.A. 20 20 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 53.7 53.4 N.A.
Protein Similarity: N.A. N.A. N.A. 70.2 70.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 15 8 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 15 36 43 15 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 8 8 8 43 % F
% Gly: 0 8 0 0 0 8 0 0 0 15 0 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 15 29 0 % H
% Ile: 8 0 36 36 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 43 29 29 0 0 8 0 15 0 8 8 0 8 0 0 % K
% Leu: 0 8 8 58 43 0 0 0 0 0 0 8 0 0 15 % L
% Met: 0 0 0 0 29 29 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 8 8 8 22 29 0 8 8 22 22 0 0 0 % N
% Pro: 0 0 0 0 0 15 22 8 0 0 15 8 8 43 29 % P
% Gln: 8 0 0 0 0 0 0 8 8 8 0 0 22 0 0 % Q
% Arg: 8 8 0 0 0 0 8 8 43 29 0 0 0 0 0 % R
% Ser: 15 0 0 0 8 8 29 36 22 0 8 36 29 0 0 % S
% Thr: 8 22 8 0 8 0 0 8 0 0 0 8 0 0 0 % T
% Val: 0 22 8 0 8 0 0 8 0 0 0 0 15 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _