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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERGIC2 All Species: 13.33
Human Site: S166 Identified Species: 26.67
UniProt: Q96RQ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RQ1 NP_057654.2 377 42549 S166 R E D D S S Q S P N A C R I H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105686 378 42682 S167 R E D D S S Q S P D A C R I H
Dog Lupus familis XP_534852 377 42463 P166 R E D D S S Q P P D A C R I R
Cat Felis silvestris
Mouse Mus musculus Q9CR89 377 42463 T166 R E D D S S L T P D A C R I H
Rat Rattus norvegicus NP_001020155 109 12522
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508860 384 43411 P166 R G D L S L Q P P D A C R I H
Chicken Gallus gallus XP_415941 377 42503 S166 R E D N S L E S P D A C R I H
Frog Xenopus laevis Q66KH2 389 44134 R168 D D V R E A Y R R K G W A F K
Zebra Danio Brachydanio rerio Q7T2D4 376 42572 L166 E D D P N Q P L N A C R I H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395190 389 44263 Y165 K R T H Q P I Y A P N A C R I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192079 388 43147 K166 P Q R V D S G K K L D A C R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04651 352 40687 H163 L P E F N G C H V F G S I P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.8 96.2 N.A. 95.4 27.3 N.A. 69.5 88.3 30.3 78.5 N.A. N.A. 41.3 N.A. 52.8
Protein Similarity: 100 N.A. 97.6 98.4 N.A. 97.8 28.6 N.A. 77 94.9 46 88 N.A. N.A. 61.7 N.A. 72.6
P-Site Identity: 100 N.A. 93.3 80 N.A. 80 0 N.A. 66.6 73.3 0 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 N.A. 100 86.6 N.A. 93.3 0 N.A. 73.3 93.3 13.3 20 N.A. N.A. 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 0 9 9 50 17 9 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 9 50 17 0 0 % C
% Asp: 9 17 59 34 9 0 0 0 0 42 9 0 0 0 0 % D
% Glu: 9 42 9 0 9 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 9 0 0 0 9 0 % F
% Gly: 0 9 0 0 0 9 9 0 0 0 17 0 0 0 9 % G
% His: 0 0 0 9 0 0 0 9 0 0 0 0 0 9 42 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 0 17 50 9 % I
% Lys: 9 0 0 0 0 0 0 9 9 9 0 0 0 0 9 % K
% Leu: 9 0 0 9 0 17 9 9 0 9 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 17 0 0 0 9 9 9 0 0 0 0 % N
% Pro: 9 9 0 9 0 9 9 17 50 9 0 0 0 9 0 % P
% Gln: 0 9 0 0 9 9 34 0 0 0 0 0 0 0 0 % Q
% Arg: 50 9 9 9 0 0 0 9 9 0 0 9 50 17 9 % R
% Ser: 0 0 0 0 50 42 0 25 0 0 0 9 0 0 0 % S
% Thr: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % T
% Val: 0 0 9 9 0 0 0 0 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _