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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCCC1
All Species:
16.36
Human Site:
S109
Identified Species:
30
UniProt:
Q96RQ3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RQ3
NP_064551.3
725
80473
S109
P
S
Q
Q
S
Y
L
S
M
E
K
I
I
Q
V
Chimpanzee
Pan troglodytes
XP_516898
856
95175
S240
P
S
Q
Q
S
Y
L
S
M
E
K
I
I
Q
V
Rhesus Macaque
Macaca mulatta
XP_001096717
797
88697
S181
P
S
Q
Q
S
Y
L
S
M
E
K
I
I
Q
V
Dog
Lupus familis
XP_535817
725
80093
S109
P
S
Q
Q
S
Y
L
S
M
E
K
I
I
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR8
717
79325
K108
Q
S
Y
L
A
M
E
K
I
I
Q
V
A
K
S
Rat
Rattus norvegicus
Q5I0C3
715
79311
K108
Q
S
Y
L
A
M
E
K
I
I
Q
V
A
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505307
696
77115
E107
P
G
Y
G
F
L
S
E
N
T
E
F
A
E
L
Chicken
Gallus gallus
NP_001006551
713
78396
Q106
L
A
V
E
K
I
I
Q
V
A
K
T
S
A
A
Frog
Xenopus laevis
NP_001086068
716
79481
L108
Y
L
A
M
D
K
I
L
Q
V
A
K
R
S
G
Zebra Danio
Brachydanio rerio
NP_001139085
711
78049
S107
I
L
D
V
A
K
K
S
S
A
Q
A
V
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651896
698
76496
G106
G
A
Q
A
I
H
P
G
Y
G
F
L
S
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19842
724
79744
R109
P
T
A
K
S
Y
L
R
A
D
R
I
L
Q
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42523
734
80433
T109
I
M
E
A
A
A
R
T
G
A
Q
A
I
H
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
88.5
88
N.A.
84.1
83.4
N.A.
78.6
76.1
74.6
70.6
N.A.
52.8
N.A.
39.4
N.A.
Protein Similarity:
100
84.1
89.7
94
N.A.
90.3
89.6
N.A.
86
85.9
84.4
82.3
N.A.
69.3
N.A.
58.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
6.6
6.6
0
6.6
N.A.
6.6
N.A.
40
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
40
N.A.
26.6
33.3
6.6
26.6
N.A.
33.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
16
16
31
8
0
0
8
24
8
16
24
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
8
8
0
0
16
8
0
31
8
0
0
16
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
8
8
0
8
0
0
0
8
8
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
16
0
% H
% Ile:
16
0
0
0
8
8
16
0
16
16
0
39
39
0
0
% I
% Lys:
0
0
0
8
8
16
8
16
0
0
39
8
0
16
0
% K
% Leu:
8
16
0
16
0
8
39
8
0
0
0
8
8
0
8
% L
% Met:
0
8
0
8
0
16
0
0
31
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
47
0
0
0
0
0
8
0
0
0
0
0
0
0
16
% P
% Gln:
16
0
39
31
0
0
0
8
8
0
31
0
0
39
0
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
8
0
8
0
0
% R
% Ser:
0
47
0
0
39
0
8
39
8
0
0
0
16
8
24
% S
% Thr:
0
8
0
0
0
0
0
8
0
8
0
8
0
0
0
% T
% Val:
0
0
8
8
0
0
0
0
8
8
0
16
8
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
24
0
0
39
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _