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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCCC1 All Species: 31.82
Human Site: S164 Identified Species: 58.33
UniProt: Q96RQ3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RQ3 NP_064551.3 725 80473 S164 I R D M G I K S T S K S I M A
Chimpanzee Pan troglodytes XP_516898 856 95175 S295 I R D M G I K S T S K S I M A
Rhesus Macaque Macaca mulatta XP_001096717 797 88697 S236 I R D M G I K S T S K S I M A
Dog Lupus familis XP_535817 725 80093 S164 I K D M G I K S T S K S I M A
Cat Felis silvestris
Mouse Mus musculus Q99MR8 717 79325 S160 I R D M G I K S T S K S I M A
Rat Rattus norvegicus Q5I0C3 715 79311 S160 I R D M G I K S T S K S I M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505307 696 77115 H155 V P I V E G Y H G E D Q S D R
Chicken Gallus gallus NP_001006551 713 78396 S155 I R D M G I K S T S K A I M S
Frog Xenopus laevis NP_001086068 716 79481 S158 I R D M G I K S T S K A I M S
Zebra Danio Brachydanio rerio NP_001139085 711 78049 I156 I K S T S K H I M S A A G V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651896 698 76496 P154 I M A A A G V P I I N G Y H G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19842 724 79744 I164 I L D M G D K I H S K K I A T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42523 734 80433 I158 D K S A S K R I M G A A G V P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.8 88.5 88 N.A. 84.1 83.4 N.A. 78.6 76.1 74.6 70.6 N.A. 52.8 N.A. 39.4 N.A.
Protein Similarity: 100 84.1 89.7 94 N.A. 90.3 89.6 N.A. 86 85.9 84.4 82.3 N.A. 69.3 N.A. 58.7 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 0 86.6 86.6 13.3 N.A. 6.6 N.A. 53.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 100 33.3 N.A. 6.6 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 62.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 16 8 0 0 0 0 0 16 31 0 8 47 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 70 0 0 8 0 0 0 0 8 0 0 8 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 70 16 0 0 8 8 0 8 16 0 8 % G
% His: 0 0 0 0 0 0 8 8 8 0 0 0 0 8 0 % H
% Ile: 85 0 8 0 0 62 0 24 8 8 0 0 70 0 0 % I
% Lys: 0 24 0 0 0 16 70 0 0 0 70 8 0 0 0 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 8 0 70 0 0 0 0 16 0 0 0 0 62 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 16 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 54 0 0 0 0 8 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 16 0 16 0 0 62 0 77 0 47 8 0 16 % S
% Thr: 0 0 0 8 0 0 0 0 62 0 0 0 0 0 8 % T
% Val: 8 0 0 8 0 0 8 0 0 0 0 0 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _