KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCCC1
All Species:
14.24
Human Site:
S24
Identified Species:
26.11
UniProt:
Q96RQ3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RQ3
NP_064551.3
725
80473
S24
N
R
W
H
R
L
P
S
L
L
L
P
P
R
T
Chimpanzee
Pan troglodytes
XP_516898
856
95175
S155
N
R
W
H
R
L
P
S
L
L
L
P
P
R
T
Rhesus Macaque
Macaca mulatta
XP_001096717
797
88697
S96
N
R
W
H
R
L
P
S
L
L
L
P
P
R
T
Dog
Lupus familis
XP_535817
725
80093
S24
N
R
W
L
R
V
P
S
L
L
L
A
P
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR8
717
79325
P25
V
P
I
L
L
L
Q
P
R
E
W
A
W
K
L
Rat
Rattus norvegicus
Q5I0C3
715
79311
P25
V
P
I
L
L
L
Q
P
R
E
W
P
W
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505307
696
77115
K24
L
E
G
N
K
I
A
K
V
L
I
A
N
R
G
Chicken
Gallus gallus
NP_001006551
713
78396
S23
P
L
Q
R
Q
P
W
S
P
V
Q
L
L
A
K
Frog
Xenopus laevis
NP_001086068
716
79481
Q24
S
V
L
L
H
R
R
Q
W
T
C
G
P
K
L
Zebra Danio
Brachydanio rerio
NP_001139085
711
78049
T24
H
L
L
T
L
I
W
T
K
G
F
V
R
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651896
698
76496
K23
F
A
T
E
A
S
P
K
V
R
P
I
S
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19842
724
79744
P24
A
T
A
A
V
A
R
P
G
V
P
L
D
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42523
734
80433
R23
K
N
H
S
M
L
V
R
Y
I
S
G
S
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
88.5
88
N.A.
84.1
83.4
N.A.
78.6
76.1
74.6
70.6
N.A.
52.8
N.A.
39.4
N.A.
Protein Similarity:
100
84.1
89.7
94
N.A.
90.3
89.6
N.A.
86
85.9
84.4
82.3
N.A.
69.3
N.A.
58.7
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
6.6
13.3
N.A.
13.3
6.6
6.6
0
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
13.3
20
N.A.
46.6
20
20
20
N.A.
20
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
8
8
8
0
0
0
0
24
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
16
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
8
8
0
16
0
8
16
% G
% His:
8
0
8
24
8
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
16
0
0
16
0
0
0
8
8
8
0
0
8
% I
% Lys:
8
0
0
0
8
0
0
16
8
0
0
0
0
31
8
% K
% Leu:
8
16
16
31
24
47
0
0
31
39
31
16
8
0
16
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
31
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
16
0
0
0
8
39
24
8
0
16
31
39
0
0
% P
% Gln:
0
0
8
0
8
0
16
8
0
0
8
0
0
0
0
% Q
% Arg:
0
31
0
8
31
8
16
8
16
8
0
0
8
31
16
% R
% Ser:
8
0
0
8
0
8
0
39
0
0
8
0
16
0
8
% S
% Thr:
0
8
8
8
0
0
0
8
0
8
0
0
0
0
24
% T
% Val:
16
8
0
0
8
8
8
0
16
16
0
8
0
0
0
% V
% Trp:
0
0
31
0
0
0
16
0
8
0
16
0
16
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _