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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCCC1
All Species:
34.24
Human Site:
S540
Identified Species:
62.78
UniProt:
Q96RQ3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RQ3
NP_064551.3
725
80473
S540
Q
F
S
P
F
S
S
S
S
G
R
R
L
N
I
Chimpanzee
Pan troglodytes
XP_516898
856
95175
S671
Q
F
S
P
F
S
S
S
S
G
R
R
L
N
I
Rhesus Macaque
Macaca mulatta
XP_001096717
797
88697
S612
Q
F
S
P
F
S
S
S
S
G
R
R
L
N
I
Dog
Lupus familis
XP_535817
725
80093
S540
Q
Y
S
P
F
A
S
S
S
G
R
R
L
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR8
717
79325
F535
D
Q
F
S
P
F
S
F
S
S
G
R
R
L
N
Rat
Rattus norvegicus
Q5I0C3
715
79311
P532
H
T
Q
D
Q
F
S
P
F
S
F
S
S
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505307
696
77115
S513
R
F
S
P
F
A
S
S
S
G
R
R
L
N
V
Chicken
Gallus gallus
NP_001006551
713
78396
S531
K
F
S
P
F
A
F
S
T
G
R
R
I
N
I
Frog
Xenopus laevis
NP_001086068
716
79481
S534
P
F
S
P
F
A
F
S
N
G
R
R
I
N
V
Zebra Danio
Brachydanio rerio
NP_001139085
711
78049
S527
V
F
S
P
F
A
S
S
N
G
R
R
L
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651896
698
76496
T515
D
Q
D
P
F
V
A
T
P
N
A
R
L
N
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19842
724
79744
S542
Q
R
S
T
H
V
A
S
F
S
K
T
Y
K
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42523
734
80433
W534
H
G
K
V
P
S
I
W
Y
S
N
P
P
F
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
88.5
88
N.A.
84.1
83.4
N.A.
78.6
76.1
74.6
70.6
N.A.
52.8
N.A.
39.4
N.A.
Protein Similarity:
100
84.1
89.7
94
N.A.
90.3
89.6
N.A.
86
85.9
84.4
82.3
N.A.
69.3
N.A.
58.7
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
20
6.6
N.A.
80
66.6
60
73.3
N.A.
33.3
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
6.6
N.A.
100
93.3
86.6
93.3
N.A.
46.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
39
16
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
54
8
0
70
16
16
8
16
0
8
0
0
8
8
% F
% Gly:
0
8
0
0
0
0
0
0
0
62
8
0
0
8
0
% G
% His:
16
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
16
0
39
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
54
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
16
8
8
0
0
70
8
% N
% Pro:
8
0
0
70
16
0
0
8
8
0
0
8
8
0
0
% P
% Gln:
39
16
8
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
0
0
62
77
8
0
16
% R
% Ser:
0
0
70
8
0
31
62
70
47
31
0
8
8
0
0
% S
% Thr:
0
8
0
8
0
0
0
8
8
0
0
8
0
0
0
% T
% Val:
8
0
0
8
0
16
0
0
0
0
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _