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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCCC1
All Species:
13.64
Human Site:
S719
Identified Species:
25
UniProt:
Q96RQ3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RQ3
NP_064551.3
725
80473
S719
V
E
F
E
E
E
E
S
D
K
R
E
S
E
_
Chimpanzee
Pan troglodytes
XP_516898
856
95175
S850
V
E
F
E
E
E
E
S
D
K
R
E
S
E
_
Rhesus Macaque
Macaca mulatta
XP_001096717
797
88697
S791
V
E
F
E
E
E
E
S
D
K
R
E
S
E
_
Dog
Lupus familis
XP_535817
725
80093
S719
I
E
F
E
E
E
E
S
D
K
R
K
T
E
_
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR8
717
79325
Rat
Rattus norvegicus
Q5I0C3
715
79311
E709
N
R
H
A
P
L
V
E
F
E
E
E
E
V
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505307
696
77115
E690
Q
L
V
E
F
V
E
E
E
T
E
K
S
E
_
Chicken
Gallus gallus
NP_001006551
713
78396
Frog
Xenopus laevis
NP_001086068
716
79481
Zebra Danio
Brachydanio rerio
NP_001139085
711
78049
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651896
698
76496
V692
G
A
A
V
I
T
F
V
D
E
E
V
E
K
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19842
724
79744
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42523
734
80433
A719
I
Q
D
L
K
V
K
A
G
Q
Q
V
S
D
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
88.5
88
N.A.
84.1
83.4
N.A.
78.6
76.1
74.6
70.6
N.A.
52.8
N.A.
39.4
N.A.
Protein Similarity:
100
84.1
89.7
94
N.A.
90.3
89.6
N.A.
86
85.9
84.4
82.3
N.A.
69.3
N.A.
58.7
N.A.
P-Site Identity:
100
100
100
78.5
N.A.
0
7.1
N.A.
28.5
0
0
0
N.A.
7.1
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
0
14.2
N.A.
42.8
0
0
0
N.A.
21.4
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
39
0
0
0
0
8
0
% D
% Glu:
0
31
0
39
31
31
39
16
8
16
24
31
16
39
0
% E
% Phe:
0
0
31
0
8
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
8
0
0
31
0
16
0
8
0
% K
% Leu:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
31
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
31
0
0
0
0
39
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% T
% Val:
24
0
8
8
0
16
8
8
0
0
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% _