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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCCC1 All Species: 30.91
Human Site: T414 Identified Species: 56.67
UniProt: Q96RQ3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RQ3 NP_064551.3 725 80473 T414 T P R A D P S T R I E T G V R
Chimpanzee Pan troglodytes XP_516898 856 95175 T545 T P R A D P S T R I E T G V R
Rhesus Macaque Macaca mulatta XP_001096717 797 88697 T486 T P P A D P S T R I E T G V R
Dog Lupus familis XP_535817 725 80093 T414 T P Q G D L C T R I E T G V R
Cat Felis silvestris
Mouse Mus musculus Q99MR8 717 79325 T410 T P S A D M S T R I E T G V R
Rat Rattus norvegicus Q5I0C3 715 79311 T410 T P P P D M S T R I E T G V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505307 696 77115 V387 T P P A T S S V R I E T G V R
Chicken Gallus gallus NP_001006551 713 78396 T405 T P P S D R D T R I E T G V R
Frog Xenopus laevis NP_001086068 716 79481 T408 T P P S D V F T R I E T G V R
Zebra Danio Brachydanio rerio NP_001139085 711 78049 T401 T P P G D Q N T R I E T G V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651896 698 76496 V393 T P Q P S N N V R V E T G V R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19842 724 79744 V415 E P K H V D G V R C D S G I R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42523 734 80433 V404 P V A V S P S V R V E T G V E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.8 88.5 88 N.A. 84.1 83.4 N.A. 78.6 76.1 74.6 70.6 N.A. 52.8 N.A. 39.4 N.A.
Protein Similarity: 100 84.1 89.7 94 N.A. 90.3 89.6 N.A. 86 85.9 84.4 82.3 N.A. 69.3 N.A. 58.7 N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 86.6 80 N.A. 73.3 73.3 73.3 73.3 N.A. 53.3 N.A. 26.6 N.A.
P-Site Similarity: 100 100 93.3 80 N.A. 86.6 80 N.A. 73.3 80 80 80 N.A. 73.3 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 62.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 39 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 70 8 8 0 0 0 8 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 93 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 16 0 0 8 0 0 0 0 0 100 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 77 0 0 0 8 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 16 0 0 0 0 0 0 0 0 % N
% Pro: 8 93 47 16 0 31 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 16 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 16 0 0 8 0 0 100 0 0 0 0 0 93 % R
% Ser: 0 0 8 16 16 8 54 0 0 0 0 8 0 0 0 % S
% Thr: 85 0 0 0 8 0 0 70 0 0 0 93 0 0 0 % T
% Val: 0 8 0 8 8 8 0 31 0 16 0 0 0 93 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _