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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCCC1
All Species:
20.3
Human Site:
T645
Identified Species:
37.22
UniProt:
Q96RQ3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RQ3
NP_064551.3
725
80473
T645
S
S
V
S
S
Q
E
T
Q
G
G
P
L
A
P
Chimpanzee
Pan troglodytes
XP_516898
856
95175
T776
S
S
V
S
S
Q
E
T
K
G
G
P
L
A
P
Rhesus Macaque
Macaca mulatta
XP_001096717
797
88697
T717
S
S
V
S
S
E
G
T
Q
G
G
P
L
A
P
Dog
Lupus familis
XP_535817
725
80093
T645
S
S
M
S
S
G
G
T
Q
G
G
T
I
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR8
717
79325
G640
L
S
P
V
S
A
E
G
A
Q
G
G
T
I
A
Rat
Rattus norvegicus
Q5I0C3
715
79311
S637
P
K
Y
L
S
P
V
S
A
E
G
T
Q
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505307
696
77115
A618
S
G
V
S
T
S
A
A
Q
G
G
A
I
A
P
Chicken
Gallus gallus
NP_001006551
713
78396
T636
S
A
V
S
S
A
G
T
Q
G
G
A
V
A
P
Frog
Xenopus laevis
NP_001086068
716
79481
T639
S
E
V
S
T
T
G
T
Q
G
G
A
V
A
P
Zebra Danio
Brachydanio rerio
NP_001139085
711
78049
A632
A
G
V
S
G
S
S
A
Q
G
G
A
V
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651896
698
76496
G620
S
A
Q
G
D
Q
L
G
A
V
G
S
R
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19842
724
79744
K647
V
K
Y
L
Q
Y
M
K
E
K
A
K
V
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42523
734
80433
K639
E
H
H
Q
F
K
Q
K
V
G
I
E
F
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
88.5
88
N.A.
84.1
83.4
N.A.
78.6
76.1
74.6
70.6
N.A.
52.8
N.A.
39.4
N.A.
Protein Similarity:
100
84.1
89.7
94
N.A.
90.3
89.6
N.A.
86
85.9
84.4
82.3
N.A.
69.3
N.A.
58.7
N.A.
P-Site Identity:
100
93.3
86.6
66.6
N.A.
26.6
13.3
N.A.
53.3
66.6
60
46.6
N.A.
20
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
26.6
20
N.A.
66.6
80
73.3
60
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
0
16
8
16
24
0
8
31
0
62
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
8
0
0
0
8
24
0
8
8
0
8
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
16
0
8
8
8
31
16
0
70
85
8
0
8
8
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
16
16
0
% I
% Lys:
0
16
0
0
0
8
0
16
8
8
0
8
0
0
0
% K
% Leu:
8
0
0
16
0
0
8
0
0
0
0
0
24
0
8
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
8
0
0
0
0
0
24
0
0
62
% P
% Gln:
0
0
8
8
8
24
8
0
54
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
62
39
0
62
54
16
8
8
0
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
16
8
0
47
0
0
0
16
8
0
0
% T
% Val:
8
0
54
8
0
0
8
0
8
8
0
0
31
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _