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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCCC1 All Species: 36.67
Human Site: Y458 Identified Species: 67.22
UniProt: Q96RQ3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RQ3 NP_064551.3 725 80473 Y458 L R Y S L R Q Y N I V G L H T
Chimpanzee Pan troglodytes XP_516898 856 95175 Y589 L R Y S L R Q Y N I V G L H T
Rhesus Macaque Macaca mulatta XP_001096717 797 88697 Y530 L R Y S L R Q Y N I I G L H T
Dog Lupus familis XP_535817 725 80093 Y458 L R Y S L R Q Y H I V G L H T
Cat Felis silvestris
Mouse Mus musculus Q99MR8 717 79325 Y454 L R Y C L H Q Y N I V G L R S
Rat Rattus norvegicus Q5I0C3 715 79311 S450 A L S K L R Y S L H Q Y N I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505307 696 77115 Y431 L R Y S L R Q Y N I T G L N T
Chicken Gallus gallus NP_001006551 713 78396 Y449 L R Y S L H Q Y N I V G L S T
Frog Xenopus laevis NP_001086068 716 79481 Y452 L K Y C L H Q Y N I V G L N T
Zebra Danio Brachydanio rerio NP_001139085 711 78049 Y445 L R Y C L R Q Y N I V G L N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651896 698 76496 R433 A L N S L V A R L G E Y H I S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19842 724 79744 Y459 M Q E A L D N Y V I R G V T H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42523 734 80433 F448 L K D C L S N F Q V A G V P T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.8 88.5 88 N.A. 84.1 83.4 N.A. 78.6 76.1 74.6 70.6 N.A. 52.8 N.A. 39.4 N.A.
Protein Similarity: 100 84.1 89.7 94 N.A. 90.3 89.6 N.A. 86 85.9 84.4 82.3 N.A. 69.3 N.A. 58.7 N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 73.3 13.3 N.A. 86.6 86.6 73.3 86.6 N.A. 13.3 N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 80 13.3 N.A. 93.3 86.6 86.6 93.3 N.A. 20 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 62.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 0 0 8 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 31 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 85 0 0 0 % G
% His: 0 0 0 0 0 24 0 0 8 8 0 0 8 31 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 77 8 0 0 16 0 % I
% Lys: 0 16 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 77 16 0 0 100 0 0 0 16 0 0 0 70 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 16 0 62 0 0 0 8 24 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 8 0 0 0 0 70 0 8 0 8 0 0 0 0 % Q
% Arg: 0 62 0 0 0 54 0 8 0 0 8 0 0 8 0 % R
% Ser: 0 0 8 54 0 8 0 8 0 0 0 0 0 8 16 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 70 % T
% Val: 0 0 0 0 0 8 0 0 8 8 54 0 16 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 70 0 0 0 8 77 0 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _