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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERBB2IP All Species: 18.18
Human Site: S659 Identified Species: 40
UniProt: Q96RT1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RT1 NP_001006600.1 1412 158298 S659 N Q N N S N C S S P S R M S D
Chimpanzee Pan troglodytes XP_001162761 1412 158257 S659 N Q N N S N C S S P S R M S D
Rhesus Macaque Macaca mulatta XP_001088781 1458 163156 S659 N Q N N S N C S S P S R M S D
Dog Lupus familis XP_535260 1302 145834 A581 P V T T N M K A S E N L K H I
Cat Felis silvestris
Mouse Mus musculus Q80TH2 1402 157214 S656 N Q N N S N C S S P S R M S D
Rat Rattus norvegicus P70587 1495 167465 P733 L W G N R I A P P F P Q P L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520661 1469 160728 S657 N Q N N S N C S S P S R M S D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q4H4B6 1724 189501 A689 P F Q H R L D A A E L E D I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KRY7 1851 200421 L654 S E I L A N A L A S Q E R N D
Honey Bee Apis mellifera XP_393738 980 109823 V259 I H I I P S E V E G W R D I S
Nematode Worm Caenorhab. elegans O61967 699 77331
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.7 85.9 N.A. 88.8 40.6 N.A. 73.7 N.A. N.A. 25.8 N.A. 24.2 29.1 21.2 N.A.
Protein Similarity: 100 99.8 95.7 88.9 N.A. 93.1 57.3 N.A. 81.6 N.A. N.A. 42.7 N.A. 40.9 44.9 34.3 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 13.3 N.A. 100 N.A. N.A. 0 N.A. 13.3 6.6 0 N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 100 20 N.A. 100 N.A. N.A. 20 N.A. 46.6 13.3 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 19 19 19 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 46 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 19 0 64 % D
% Glu: 0 10 0 0 0 0 10 0 10 19 0 19 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 10 0 10 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 10 0 19 10 0 10 0 0 0 0 0 0 0 19 10 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % K
% Leu: 10 0 0 10 0 10 0 10 0 0 10 10 0 10 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 46 0 0 % M
% Asn: 46 0 46 55 10 55 0 0 0 0 10 0 0 10 0 % N
% Pro: 19 0 0 0 10 0 0 10 10 46 10 0 10 0 0 % P
% Gln: 0 46 10 0 0 0 0 0 0 0 10 10 0 0 0 % Q
% Arg: 0 0 0 0 19 0 0 0 0 0 0 55 10 0 10 % R
% Ser: 10 0 0 0 46 10 0 46 55 10 46 0 0 46 10 % S
% Thr: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _