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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERBB2IP All Species: 20.91
Human Site: T220 Identified Species: 46
UniProt: Q96RT1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RT1 NP_001006600.1 1412 158298 T220 W M D A N R L T F I P G F I G
Chimpanzee Pan troglodytes XP_001162761 1412 158257 T220 W M D A N R L T F I P G F I G
Rhesus Macaque Macaca mulatta XP_001088781 1458 163156 T220 W M D A N R L T F I P G F I G
Dog Lupus familis XP_535260 1302 145834 Q172 I L E L R E N Q L K M L P K T
Cat Felis silvestris
Mouse Mus musculus Q80TH2 1402 157214 T220 W M D G N R L T F I P G F I G
Rat Rattus norvegicus P70587 1495 167465 Q225 W M D N N A L Q V L P G S I G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520661 1469 160728 S220 W M D G N R L S F I P G F L G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q4H4B6 1724 189501 S210 W L D R N Q L S S L P P E L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KRY7 1851 200421 Q211 W L D H N Q L Q R L P P E L G
Honey Bee Apis mellifera XP_393738 980 109823
Nematode Worm Caenorhab. elegans O61967 699 77331
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.7 85.9 N.A. 88.8 40.6 N.A. 73.7 N.A. N.A. 25.8 N.A. 24.2 29.1 21.2 N.A.
Protein Similarity: 100 99.8 95.7 88.9 N.A. 93.1 57.3 N.A. 81.6 N.A. N.A. 42.7 N.A. 40.9 44.9 34.3 N.A.
P-Site Identity: 100 100 100 0 N.A. 93.3 60 N.A. 80 N.A. N.A. 40 N.A. 40 0 0 N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 93.3 66.6 N.A. 93.3 N.A. N.A. 73.3 N.A. 66.6 0 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 28 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 73 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 10 0 0 0 0 0 0 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 46 0 0 0 46 0 0 % F
% Gly: 0 0 0 19 0 0 0 0 0 0 0 55 0 0 73 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 46 0 0 0 46 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % K
% Leu: 0 28 0 10 0 0 73 0 10 28 0 10 0 28 0 % L
% Met: 0 55 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 10 73 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 73 19 10 0 0 % P
% Gln: 0 0 0 0 0 19 0 28 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 10 46 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 19 10 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 37 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _