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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERBB2IP
All Species:
13.94
Human Site:
T541
Identified Species:
30.67
UniProt:
Q96RT1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RT1
NP_001006600.1
1412
158298
T541
K
T
S
E
S
T
T
T
V
K
S
K
V
D
E
Chimpanzee
Pan troglodytes
XP_001162761
1412
158257
T541
K
T
S
E
S
T
T
T
V
K
S
K
V
D
E
Rhesus Macaque
Macaca mulatta
XP_001088781
1458
163156
T541
K
T
S
E
S
T
T
T
V
K
S
K
V
D
E
Dog
Lupus familis
XP_535260
1302
145834
D465
A
Q
V
A
F
D
C
D
E
D
K
D
E
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80TH2
1402
157214
S538
K
C
V
K
T
S
E
S
T
T
T
K
S
K
L
Rat
Rattus norvegicus
P70587
1495
167465
N609
E
N
A
N
P
T
A
N
T
E
Q
T
V
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520661
1469
160728
P539
V
K
T
S
E
G
I
P
V
K
G
Q
T
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q4H4B6
1724
189501
S532
Q
A
S
S
S
T
T
S
A
T
S
H
E
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY7
1851
200421
R512
A
E
T
P
T
E
T
R
T
I
A
N
N
H
Q
Honey Bee
Apis mellifera
XP_393738
980
109823
D142
N
P
F
E
R
F
P
D
A
I
T
H
I
V
G
Nematode Worm
Caenorhab. elegans
O61967
699
77331
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.7
85.9
N.A.
88.8
40.6
N.A.
73.7
N.A.
N.A.
25.8
N.A.
24.2
29.1
21.2
N.A.
Protein Similarity:
100
99.8
95.7
88.9
N.A.
93.1
57.3
N.A.
81.6
N.A.
N.A.
42.7
N.A.
40.9
44.9
34.3
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
13.3
20
N.A.
13.3
N.A.
N.A.
40
N.A.
6.6
6.6
0
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
46.6
40
N.A.
40
N.A.
N.A.
60
N.A.
33.3
20
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
10
10
0
0
10
0
19
0
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
19
0
10
0
10
0
37
10
% D
% Glu:
10
10
0
37
10
10
10
0
10
10
0
0
19
10
46
% E
% Phe:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
19
0
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
19
0
0
10
0
0
% I
% Lys:
37
10
0
10
0
0
0
0
0
37
10
37
0
19
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
0
0
10
0
0
0
10
10
0
0
% N
% Pro:
0
10
0
10
10
0
10
10
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
10
10
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% R
% Ser:
0
0
37
19
37
10
0
19
0
0
37
0
10
0
0
% S
% Thr:
0
28
19
0
19
46
46
28
28
19
19
10
10
0
0
% T
% Val:
10
0
19
0
0
0
0
0
37
0
0
0
37
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _