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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP28 All Species: 18.18
Human Site: S1059 Identified Species: 44.44
UniProt: Q96RU2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.44
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RU2 NP_065937.1 1077 122491 S1059 N S P Y D L C S R F A A V M E
Chimpanzee Pan troglodytes XP_531393 1087 125791 E1070 Y S T H E L C E R F A R I M L
Rhesus Macaque Macaca mulatta XP_001085291 1077 122559 S1059 N S P Y D L C S R F A A V M E
Dog Lupus familis XP_546518 1078 122398 S1060 N S P Y D L C S R F A A V M E
Cat Felis silvestris
Mouse Mus musculus Q5I043 1051 119299 N1033 N S P Y D L C N R F A A V M E
Rat Rattus norvegicus NP_001101614 1079 122194 S1061 N S P Y D L C S R F A A V M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514451 1105 126985 E1088 Y S T H E L C E R F A G V M L
Chicken Gallus gallus Q5ZID5 1047 118729 S1029 N S P Y D L C S R F A A V M E
Frog Xenopus laevis NP_001086746 1046 121273 E1029 F S T H E L C E R F A R I M L
Zebra Danio Brachydanio rerio NP_001001886 1072 123104 E1053 Y S T L E L F E R F G R V M T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.2 99.1 93.4 N.A. 88 91.2 N.A. 48.6 64.8 50.7 50.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 68.8 99.4 95.9 N.A. 92.1 95 N.A. 65.2 76.1 68.5 68 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 46.6 100 100 N.A. 93.3 100 N.A. 53.3 100 46.6 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 100 N.A. 100 100 N.A. 66.6 100 66.6 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 90 60 0 0 0 % A
% Cys: 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 40 0 0 40 0 0 0 0 0 0 60 % E
% Phe: 10 0 0 0 0 0 10 0 0 100 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % G
% His: 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 100 0 0 0 0 0 0 0 0 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % M
% Asn: 60 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 100 0 0 30 0 0 0 % R
% Ser: 0 100 0 0 0 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 0 40 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 30 0 0 60 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _