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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP28
All Species:
10.61
Human Site:
S460
Identified Species:
25.93
UniProt:
Q96RU2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RU2
NP_065937.1
1077
122491
S460
S
T
K
P
A
S
E
S
C
P
P
E
S
D
T
Chimpanzee
Pan troglodytes
XP_531393
1087
125791
S467
S
S
K
P
V
C
T
S
P
V
D
D
I
D
A
Rhesus Macaque
Macaca mulatta
XP_001085291
1077
122559
S460
S
T
K
P
A
S
E
S
C
P
P
E
S
D
T
Dog
Lupus familis
XP_546518
1078
122398
C460
P
A
S
E
S
P
T
C
Q
S
D
A
H
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5I043
1051
119299
G465
A
S
E
S
C
L
S
G
S
A
E
H
V
T
L
Rat
Rattus norvegicus
NP_001101614
1079
122194
S457
S
T
K
P
A
S
E
S
C
L
S
G
S
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514451
1105
126985
F517
V
L
Q
Y
A
L
E
F
A
S
S
K
P
V
C
Chicken
Gallus gallus
Q5ZID5
1047
118729
L435
S
G
P
A
R
F
P
L
P
D
M
L
Q
Y
V
Frog
Xenopus laevis
NP_001086746
1046
121273
S459
Q
Y
A
L
E
F
A
S
S
K
P
V
C
T
S
Zebra Danio
Brachydanio rerio
NP_001001886
1072
123104
M456
A
D
V
L
Q
Y
A
M
E
F
A
S
S
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.2
99.1
93.4
N.A.
88
91.2
N.A.
48.6
64.8
50.7
50.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68.8
99.4
95.9
N.A.
92.1
95
N.A.
65.2
76.1
68.5
68
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
6.6
N.A.
0
66.6
N.A.
13.3
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
13.3
N.A.
20
66.6
N.A.
26.6
6.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
10
10
40
0
20
0
10
10
10
10
0
0
10
% A
% Cys:
0
0
0
0
10
10
0
10
30
0
0
0
10
0
10
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
20
10
0
30
0
% D
% Glu:
0
0
10
10
10
0
40
0
10
0
10
20
0
0
10
% E
% Phe:
0
0
0
0
0
20
0
10
0
10
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
40
0
0
0
0
0
0
10
0
10
0
10
0
% K
% Leu:
0
10
0
20
0
20
0
10
0
10
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
40
0
10
10
0
20
20
30
0
10
0
10
% P
% Gln:
10
0
10
0
10
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
20
10
10
10
30
10
50
20
20
20
10
40
0
10
% S
% Thr:
0
30
0
0
0
0
20
0
0
0
0
0
0
20
30
% T
% Val:
10
0
10
0
10
0
0
0
0
10
0
10
10
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _