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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP28 All Species: 23.94
Human Site: T534 Identified Species: 58.52
UniProt: Q96RU2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RU2 NP_065937.1 1077 122491 T534 Q P A P R T V T D E E I N F V
Chimpanzee Pan troglodytes XP_531393 1087 125791 T541 H P A P R H I T E E E L S V L
Rhesus Macaque Macaca mulatta XP_001085291 1077 122559 T534 Q P A P R T V T D E E I N F V
Dog Lupus familis XP_546518 1078 122398 T534 Q P A P R T V T D E E I N F V
Cat Felis silvestris
Mouse Mus musculus Q5I043 1051 119299 T539 P P A P R T V T D E E M N F V
Rat Rattus norvegicus NP_001101614 1079 122194 A531 E M P A P P P A P R T V T D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514451 1105 126985 T591 H P A P R H I T E E E L A V L
Chicken Gallus gallus Q5ZID5 1047 118729 Q509 L L A N S S P Q Q Q L N A P L
Frog Xenopus laevis NP_001086746 1046 121273 T533 H P A P R N I T D E E L S V L
Zebra Danio Brachydanio rerio NP_001001886 1072 123104 P530 P F T Q S R V P P D L P M H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.2 99.1 93.4 N.A. 88 91.2 N.A. 48.6 64.8 50.7 50.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 68.8 99.4 95.9 N.A. 92.1 95 N.A. 65.2 76.1 68.5 68 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 46.6 100 100 N.A. 86.6 0 N.A. 46.6 6.6 53.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 100 100 N.A. 93.3 13.3 N.A. 73.3 26.6 80 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 80 10 0 0 0 10 0 0 0 0 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 50 10 0 0 0 10 0 % D
% Glu: 10 0 0 0 0 0 0 0 20 70 70 0 0 0 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 40 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 30 0 0 0 0 20 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 30 0 0 0 0 30 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 0 0 0 0 0 0 0 20 30 0 0 40 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 10 10 0 0 % M
% Asn: 0 0 0 10 0 10 0 0 0 0 0 10 40 0 0 % N
% Pro: 20 70 10 70 10 10 20 10 20 0 0 10 0 10 10 % P
% Gln: 30 0 0 10 0 0 0 10 10 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 70 10 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 20 10 0 0 0 0 0 0 20 0 0 % S
% Thr: 0 0 10 0 0 40 0 70 0 0 10 0 10 0 0 % T
% Val: 0 0 0 0 0 0 50 0 0 0 0 10 0 30 40 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _