Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCNX All Species: 17.58
Human Site: S190 Identified Species: 32.22
UniProt: Q96RV3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RV3 NP_055797.2 2341 258676 S190 I S L S L G Q S S S L C K E G
Chimpanzee Pan troglodytes XP_510039 2300 254005 Q189 P S L S S C G Q D L P R D F S
Rhesus Macaque Macaca mulatta XP_001084081 2342 258864 S190 I S L S L G Q S S S L C K E G
Dog Lupus familis XP_537501 2332 257280 K199 Q D L A T D R K L F R L V S N
Cat Felis silvestris
Mouse Mus musculus Q9QYC1 2344 258128 S190 I S L S L G Q S S S L C K E G
Rat Rattus norvegicus NP_001163818 2343 257924 S190 I S L S L G Q S S S L C K E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423893 2312 255194 R192 S S G Q D L P R D N S D K V C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923995 2285 252748 S192 S F A S M Q P S T S L A Q D L
Tiger Blowfish Takifugu rubipres Q98UF7 1703 191329
Fruit Fly Dros. melanogaster P18490 3433 367590 S246 G S A D G G S S G G D S R S G
Honey Bee Apis mellifera XP_624687 2092 236172 F25 C S S I G A L F G T I K C V N
Nematode Worm Caenorhab. elegans NP_492790 1634 183268
Sea Urchin Strong. purpuratus XP_001195494 2799 311472 G204 S K L Q G A G G G S D T S G I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 98.7 94.4 N.A. 90.9 91.1 N.A. N.A. 84.9 N.A. 66.7 54.4 29.4 38.7 27.7 35.5
Protein Similarity: 100 98.1 99.4 96.4 N.A. 95.5 95.3 N.A. N.A. 90.8 N.A. 77.7 63 42.9 55.5 41.8 49.2
P-Site Identity: 100 20 100 6.6 N.A. 100 100 N.A. N.A. 13.3 N.A. 26.6 0 26.6 6.6 0 13.3
P-Site Similarity: 100 20 100 20 N.A. 100 100 N.A. N.A. 20 N.A. 53.3 0 33.3 20 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 16 0 0 0 0 0 8 0 0 0 % A
% Cys: 8 0 0 0 0 8 0 0 0 0 0 31 8 0 8 % C
% Asp: 0 8 0 8 8 8 0 0 16 0 16 8 8 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 % E
% Phe: 0 8 0 0 0 0 0 8 0 8 0 0 0 8 0 % F
% Gly: 8 0 8 0 24 39 16 8 24 8 0 0 0 8 39 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 31 0 0 8 0 0 0 0 0 0 8 0 0 0 8 % I
% Lys: 0 8 0 0 0 0 0 8 0 0 0 8 39 0 0 % K
% Leu: 0 0 54 0 31 8 8 0 8 8 39 8 0 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 16 % N
% Pro: 8 0 0 0 0 0 16 0 0 0 8 0 0 0 0 % P
% Gln: 8 0 0 16 0 8 31 8 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 8 8 0 0 8 8 8 0 0 % R
% Ser: 24 62 8 47 8 0 8 47 31 47 8 8 8 16 8 % S
% Thr: 0 0 0 0 8 0 0 0 8 8 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _