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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCNX
All Species:
21.52
Human Site:
S2105
Identified Species:
39.44
UniProt:
Q96RV3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RV3
NP_055797.2
2341
258676
S2105
P
T
L
G
T
S
H
S
S
H
S
V
Q
S
G
Chimpanzee
Pan troglodytes
XP_510039
2300
254005
S2064
P
T
L
G
T
S
H
S
S
H
S
V
Q
S
G
Rhesus Macaque
Macaca mulatta
XP_001084081
2342
258864
S2106
P
T
L
G
T
S
H
S
S
H
S
V
Q
S
G
Dog
Lupus familis
XP_537501
2332
257280
S2096
P
A
L
G
T
S
H
S
S
H
S
V
Q
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYC1
2344
258128
S2108
P
T
L
G
T
S
H
S
A
H
S
V
Q
S
S
Rat
Rattus norvegicus
NP_001163818
2343
257924
S2107
P
T
L
G
T
S
H
S
A
H
S
V
Q
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423893
2312
255194
P2062
G
A
H
P
T
A
L
P
A
A
H
P
P
A
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923995
2285
252748
Q2056
V
Q
S
G
L
V
R
Q
S
P
A
R
A
S
V
Tiger Blowfish
Takifugu rubipres
Q98UF7
1703
191329
Q1476
S
Q
S
S
Q
S
V
Q
S
G
L
V
R
H
S
Fruit Fly
Dros. melanogaster
P18490
3433
367590
L2860
T
G
G
E
S
G
D
L
A
P
V
F
I
S
A
Honey Bee
Apis mellifera
XP_624687
2092
236172
K1865
V
I
K
S
N
V
L
K
L
W
Q
R
I
R
R
Nematode Worm
Caenorhab. elegans
NP_492790
1634
183268
I1407
Q
T
E
R
E
R
A
I
M
N
R
P
N
F
Q
Sea Urchin
Strong. purpuratus
XP_001195494
2799
311472
R2162
G
S
E
S
G
S
V
R
Q
T
P
A
H
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
98.7
94.4
N.A.
90.9
91.1
N.A.
N.A.
84.9
N.A.
66.7
54.4
29.4
38.7
27.7
35.5
Protein Similarity:
100
98.1
99.4
96.4
N.A.
95.5
95.3
N.A.
N.A.
90.8
N.A.
77.7
63
42.9
55.5
41.8
49.2
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
6.6
N.A.
20
20
6.6
0
6.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
26.6
N.A.
26.6
26.6
20
0
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
8
8
0
31
8
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
16
8
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
16
8
8
54
8
8
0
0
0
8
0
0
0
0
24
% G
% His:
0
0
8
0
0
0
47
0
0
47
8
0
8
8
8
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
16
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
47
0
8
0
16
8
8
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
47
0
0
8
0
0
0
8
0
16
8
16
8
0
0
% P
% Gln:
8
16
0
0
8
0
0
16
8
0
8
0
47
0
8
% Q
% Arg:
0
0
0
8
0
8
8
8
0
0
8
16
8
8
16
% R
% Ser:
8
8
16
24
8
62
0
47
47
0
47
0
0
70
31
% S
% Thr:
8
47
0
0
54
0
0
0
0
8
0
0
0
0
0
% T
% Val:
16
0
0
0
0
16
16
0
0
0
8
54
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _