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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCNX All Species: 26.06
Human Site: S2194 Identified Species: 47.78
UniProt: Q96RV3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RV3 NP_055797.2 2341 258676 S2194 Q H G L P S S S S S S Q S I P
Chimpanzee Pan troglodytes XP_510039 2300 254005 S2153 Q H G L P S S S S S S Q S I P
Rhesus Macaque Macaca mulatta XP_001084081 2342 258864 S2195 Q H G L P S S S S S S Q S I P
Dog Lupus familis XP_537501 2332 257280 S2185 Q H G L P S S S S S S Q S I P
Cat Felis silvestris
Mouse Mus musculus Q9QYC1 2344 258128 S2197 Q H G L P S S S S S S Q S I P
Rat Rattus norvegicus NP_001163818 2343 257924 S2196 Q H G L P S S S S S S Q S I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423893 2312 255194 T2151 M V N Q M E P T G Q S G V S M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923995 2285 252748 A2145 K R H A H T L A G L L G N E A
Tiger Blowfish Takifugu rubipres Q98UF7 1703 191329 G1565 C K R H T L V G L L G N D G L
Fruit Fly Dros. melanogaster P18490 3433 367590 T2949 G A G A S G P T R A T S S G G
Honey Bee Apis mellifera XP_624687 2092 236172 S1954 G N R G S L A S V G K P T S S
Nematode Worm Caenorhab. elegans NP_492790 1634 183268 P1496 Y T W Y P S H P L R N R R S H
Sea Urchin Strong. purpuratus XP_001195494 2799 311472 V2251 R L N I N K F V M W P D E T M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 98.7 94.4 N.A. 90.9 91.1 N.A. N.A. 84.9 N.A. 66.7 54.4 29.4 38.7 27.7 35.5
Protein Similarity: 100 98.1 99.4 96.4 N.A. 95.5 95.3 N.A. N.A. 90.8 N.A. 77.7 63 42.9 55.5 41.8 49.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 N.A. 0 0 13.3 6.6 13.3 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 N.A. 26.6 0 33.3 26.6 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 16 0 0 8 8 0 8 0 0 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 54 8 0 8 0 8 16 8 8 16 0 16 8 % G
% His: 0 47 8 8 8 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 47 0 % I
% Lys: 8 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 8 0 47 0 16 8 0 16 16 8 0 0 0 8 % L
% Met: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 16 % M
% Asn: 0 8 16 0 8 0 0 0 0 0 8 8 8 0 0 % N
% Pro: 0 0 0 0 54 0 16 8 0 0 8 8 0 0 47 % P
% Gln: 47 0 0 8 0 0 0 0 0 8 0 47 0 0 0 % Q
% Arg: 8 8 16 0 0 0 0 0 8 8 0 8 8 0 0 % R
% Ser: 0 0 0 0 16 54 47 54 47 47 54 8 54 24 8 % S
% Thr: 0 8 0 0 8 8 0 16 0 0 8 0 8 8 0 % T
% Val: 0 8 0 0 0 0 8 8 8 0 0 0 8 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _