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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCNX All Species: 15.76
Human Site: S915 Identified Species: 28.89
UniProt: Q96RV3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RV3 NP_055797.2 2341 258676 S915 D T D S H V S S S T S V R F Y
Chimpanzee Pan troglodytes XP_510039 2300 254005 D908 T D L L E Q Q D I D L S P D L
Rhesus Macaque Macaca mulatta XP_001084081 2342 258864 S916 D T D S H V S S S T S V R F Y
Dog Lupus familis XP_537501 2332 257280 V917 V R F Y P H D V L S L P Q I R
Cat Felis silvestris
Mouse Mus musculus Q9QYC1 2344 258128 S918 D T D S H V S S S T S V R F Y
Rat Rattus norvegicus NP_001163818 2343 257924 S917 D T D S H V S S S T S V R F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423893 2312 255194 S910 E Q Q D I D L S P D L Q D H L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923995 2285 252748 P912 Q D S T H N H P H T H A L A H
Tiger Blowfish Takifugu rubipres Q98UF7 1703 191329 D355 E L L E Q Q D D L S P D L Q D
Fruit Fly Dros. melanogaster P18490 3433 367590 A1204 A A N A S E A A S V S A S G A
Honey Bee Apis mellifera XP_624687 2092 236172 S743 K A Q N S L S S N P V E T S E
Nematode Worm Caenorhab. elegans NP_492790 1634 183268 K286 I H Q V A G G K E I D E N P E
Sea Urchin Strong. purpuratus XP_001195494 2799 311472 R964 L P T N I L D R L T D P H Q W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 98.7 94.4 N.A. 90.9 91.1 N.A. N.A. 84.9 N.A. 66.7 54.4 29.4 38.7 27.7 35.5
Protein Similarity: 100 98.1 99.4 96.4 N.A. 95.5 95.3 N.A. N.A. 90.8 N.A. 77.7 63 42.9 55.5 41.8 49.2
P-Site Identity: 100 0 100 0 N.A. 100 100 N.A. N.A. 6.6 N.A. 13.3 0 13.3 13.3 0 6.6
P-Site Similarity: 100 0 100 13.3 N.A. 100 100 N.A. N.A. 13.3 N.A. 26.6 13.3 40 33.3 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 8 8 0 8 8 0 0 0 16 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 31 16 31 8 0 8 24 16 0 16 16 8 8 8 8 % D
% Glu: 16 0 0 8 8 8 0 0 8 0 0 16 0 0 16 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 31 0 % F
% Gly: 0 0 0 0 0 8 8 0 0 0 0 0 0 8 0 % G
% His: 0 8 0 0 39 8 8 0 8 0 8 0 8 8 8 % H
% Ile: 8 0 0 0 16 0 0 0 8 8 0 0 0 8 0 % I
% Lys: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 8 16 8 0 16 8 0 24 0 24 0 16 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 16 0 8 0 0 8 0 0 0 8 0 0 % N
% Pro: 0 8 0 0 8 0 0 8 8 8 8 16 8 8 0 % P
% Gln: 8 8 24 0 8 16 8 0 0 0 0 8 8 16 0 % Q
% Arg: 0 8 0 0 0 0 0 8 0 0 0 0 31 0 8 % R
% Ser: 0 0 8 31 16 0 39 47 39 16 39 8 8 8 0 % S
% Thr: 8 31 8 8 0 0 0 0 0 47 0 0 8 0 0 % T
% Val: 8 0 0 8 0 31 0 8 0 8 8 31 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 31 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _