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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCNX
All Species:
24.55
Human Site:
Y2131
Identified Species:
45
UniProt:
Q96RV3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RV3
NP_055797.2
2341
258676
Y2131
A
S
Q
S
S
Y
C
Y
S
S
R
H
S
S
L
Chimpanzee
Pan troglodytes
XP_510039
2300
254005
Y2090
A
S
Q
S
S
Y
C
Y
S
S
R
H
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001084081
2342
258864
Y2132
A
S
Q
S
S
Y
C
Y
S
S
R
H
S
S
L
Dog
Lupus familis
XP_537501
2332
257280
Y2122
A
S
Q
S
S
Y
C
Y
S
S
R
H
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYC1
2344
258128
Y2134
A
S
Q
S
S
Y
C
Y
S
S
R
H
S
S
L
Rat
Rattus norvegicus
NP_001163818
2343
257924
Y2133
A
S
Q
S
S
Y
C
Y
G
S
R
H
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423893
2312
255194
R2088
S
V
Q
S
S
L
V
R
H
S
P
A
R
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923995
2285
252748
T2082
S
R
Q
S
S
L
R
T
S
V
T
G
L
E
P
Tiger Blowfish
Takifugu rubipres
Q98UF7
1703
191329
R1502
S
Y
R
Y
S
S
S
R
H
S
S
L
R
T
S
Fruit Fly
Dros. melanogaster
P18490
3433
367590
V2886
Y
S
V
R
P
G
N
V
P
G
G
P
I
P
G
Honey Bee
Apis mellifera
XP_624687
2092
236172
F1891
G
S
Q
D
D
G
G
F
G
N
D
G
V
Y
A
Nematode Worm
Caenorhab. elegans
NP_492790
1634
183268
S1433
N
Q
E
M
G
I
G
S
W
A
L
I
I
D
S
Sea Urchin
Strong. purpuratus
XP_001195494
2799
311472
R2188
G
R
R
L
N
M
G
R
V
P
I
A
N
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
98.7
94.4
N.A.
90.9
91.1
N.A.
N.A.
84.9
N.A.
66.7
54.4
29.4
38.7
27.7
35.5
Protein Similarity:
100
98.1
99.4
96.4
N.A.
95.5
95.3
N.A.
N.A.
90.8
N.A.
77.7
63
42.9
55.5
41.8
49.2
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
26.6
N.A.
26.6
13.3
6.6
13.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
40
N.A.
33.3
33.3
6.6
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
0
0
0
0
0
0
8
0
16
0
8
16
% A
% Cys:
0
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
16
24
0
16
8
8
16
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
16
0
0
47
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
8
16
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
16
0
0
0
0
8
8
8
8
47
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
8
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
8
8
8
0
8
8
% P
% Gln:
0
8
70
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
16
16
8
0
0
8
24
0
0
47
0
16
0
0
% R
% Ser:
24
62
0
62
70
8
8
8
47
62
8
0
47
47
24
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% T
% Val:
0
8
8
0
0
0
8
8
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
47
0
47
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _