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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCNX All Species: 16.36
Human Site: Y884 Identified Species: 30
UniProt: Q96RV3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RV3 NP_055797.2 2341 258676 Y884 G K F S S T L Y E T G G C D M
Chimpanzee Pan troglodytes XP_510039 2300 254005 S877 S H V S S S T S V R F Y P H D
Rhesus Macaque Macaca mulatta XP_001084081 2342 258864 Y885 G K F S S T L Y E T G G C D M
Dog Lupus familis XP_537501 2332 257280 N886 G C D M S L V N F E P A A R R
Cat Felis silvestris
Mouse Mus musculus Q9QYC1 2344 258128 Y887 G K F S S T L Y E T G G C D M
Rat Rattus norvegicus NP_001163818 2343 257924 Y886 G K F S S T L Y E T G G C D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423893 2312 255194 Y879 S S T S V H F Y P H D L L S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923995 2285 252748 M881 R L N R L L S M D P E L L E Q
Tiger Blowfish Takifugu rubipres Q98UF7 1703 191329 V324 H L S S S T S V R F Y P H D L
Fruit Fly Dros. melanogaster P18490 3433 367590 R1173 Q G L I N V I R S E R P A A R
Honey Bee Apis mellifera XP_624687 2092 236172 L712 N S Y S S L S L N S P D L S V
Nematode Worm Caenorhab. elegans NP_492790 1634 183268 H255 P D A S S P I H G F N W V A S
Sea Urchin Strong. purpuratus XP_001195494 2799 311472 S933 P R A L R A I S S T S A G G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 98.7 94.4 N.A. 90.9 91.1 N.A. N.A. 84.9 N.A. 66.7 54.4 29.4 38.7 27.7 35.5
Protein Similarity: 100 98.1 99.4 96.4 N.A. 95.5 95.3 N.A. N.A. 90.8 N.A. 77.7 63 42.9 55.5 41.8 49.2
P-Site Identity: 100 13.3 100 13.3 N.A. 100 100 N.A. N.A. 13.3 N.A. 0 26.6 0 13.3 13.3 6.6
P-Site Similarity: 100 20 100 20 N.A. 100 100 N.A. N.A. 20 N.A. 13.3 33.3 13.3 33.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 8 0 0 0 0 0 16 16 16 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 31 0 0 % C
% Asp: 0 8 8 0 0 0 0 0 8 0 8 8 0 39 8 % D
% Glu: 0 0 0 0 0 0 0 0 31 16 8 0 0 8 0 % E
% Phe: 0 0 31 0 0 0 8 0 8 16 8 0 0 0 0 % F
% Gly: 39 8 0 0 0 0 0 0 8 0 31 31 8 8 0 % G
% His: 8 8 0 0 0 8 0 8 0 8 0 0 8 8 0 % H
% Ile: 0 0 0 8 0 0 24 0 0 0 0 0 0 0 0 % I
% Lys: 0 31 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 16 8 8 8 24 31 8 0 0 0 16 24 0 16 % L
% Met: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 31 % M
% Asn: 8 0 8 0 8 0 0 8 8 0 8 0 0 0 0 % N
% Pro: 16 0 0 0 0 8 0 0 8 8 16 16 8 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 8 8 0 8 8 0 0 8 8 8 8 0 0 8 16 % R
% Ser: 16 16 8 70 70 8 24 16 16 8 8 0 0 16 8 % S
% Thr: 0 0 8 0 0 39 8 0 0 39 0 0 0 0 8 % T
% Val: 0 0 8 0 8 8 8 8 8 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 39 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _