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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A12
All Species:
13.03
Human Site:
T542
Identified Species:
31.85
UniProt:
Q96S37
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S37
NP_653186.2
553
59630
T542
V
K
K
A
T
H
G
T
L
G
N
S
V
L
K
Chimpanzee
Pan troglodytes
XP_001165302
553
59615
T542
V
K
K
A
T
H
G
T
L
G
N
S
V
L
K
Rhesus Macaque
Macaca mulatta
XP_001114815
545
58752
T534
V
K
K
A
T
H
G
T
L
G
N
S
V
L
K
Dog
Lupus familis
XP_540882
533
57582
L523
P
E
T
Q
S
L
P
L
P
D
T
I
Q
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFZ5
553
60176
T542
V
K
K
V
T
H
D
T
P
D
G
S
I
L
M
Rat
Rattus norvegicus
Q3ZAV1
553
60226
I542
V
K
K
V
T
H
D
I
A
G
G
S
V
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507099
556
61556
Q542
S
S
R
Q
Q
R
L
Q
D
P
K
Q
E
D
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J54
558
62434
E536
K
A
P
K
K
E
N
E
M
N
E
I
V
S
L
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
R539
L
A
R
T
N
S
K
R
L
P
E
K
L
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
T530
K
K
P
A
P
Q
E
T
A
E
E
G
G
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
88
80.2
N.A.
73.9
74.1
N.A.
48.3
N.A.
40.5
41.9
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
90.5
86.6
N.A.
83.5
83.9
N.A.
64.7
N.A.
63.4
63.5
N.A.
52
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
53.3
66.6
N.A.
0
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
60
66.6
N.A.
6.6
N.A.
13.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
40
0
0
0
0
20
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
20
0
10
20
0
0
0
30
0
% D
% Glu:
0
10
0
0
0
10
10
10
0
10
30
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
30
0
0
40
20
10
10
0
0
% G
% His:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
20
10
0
0
% I
% Lys:
20
60
50
10
10
0
10
0
0
0
10
10
0
0
40
% K
% Leu:
10
0
0
0
0
10
10
10
40
0
0
0
10
50
20
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
10
0
0
10
30
0
0
0
0
% N
% Pro:
10
0
20
0
10
0
10
0
20
20
0
0
0
0
0
% P
% Gln:
0
0
0
20
10
10
0
10
0
0
0
10
10
0
10
% Q
% Arg:
0
0
20
0
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
10
10
0
0
0
0
0
50
0
10
0
% S
% Thr:
0
0
10
10
50
0
0
50
0
0
10
0
0
10
0
% T
% Val:
50
0
0
20
0
0
0
0
0
0
0
0
50
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _