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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NODAL All Species: 18.79
Human Site: S36 Identified Species: 41.33
UniProt: Q96S42 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S42 NP_060525.3 347 39561 S36 L R T R G Q P S S P S P L A Y
Chimpanzee Pan troglodytes XP_521502 347 39676 S36 L R T R G Q P S S P S P L A Y
Rhesus Macaque Macaca mulatta XP_001108137 347 39778 S36 L R T R G Q P S S P S P L A Y
Dog Lupus familis XP_546146 348 39415 S37 L R A R V Q P S S P A P L A Y
Cat Felis silvestris
Mouse Mus musculus P43021 354 40430 S37 L W T R G Q P S S P S P L A Y
Rat Rattus norvegicus Q6HA10 452 50994 E110 Y R T Y S I A E K L G I N A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90751 353 40328 K31 K R R P S P G K D V V I P P Y
Frog Xenopus laevis O13048 402 46253 A75 L N H G T E G A P S L P S N H
Zebra Danio Brachydanio rerio P85857 404 46271 Y82 M I S I Y R T Y S A A E K L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_504709 365 41750 L55 H A T R R G L L R K L G L E H
Sea Urchin Strong. purpuratus P48970 395 43818 E43 L R V M G L S E R P R P K P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.5 85.3 N.A. 77.9 28.9 N.A. N.A. 26 34 25 N.A. N.A. N.A. 24.6 26
Protein Similarity: 100 99.1 97.9 88.7 N.A. 83.3 42 N.A. N.A. 43.6 49.7 42 N.A. N.A. N.A. 42.1 41
P-Site Identity: 100 100 100 80 N.A. 93.3 20 N.A. N.A. 13.3 13.3 6.6 N.A. N.A. N.A. 20 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 20 N.A. N.A. 13.3 33.3 33.3 N.A. N.A. N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 10 10 0 10 19 0 0 55 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 19 0 0 0 10 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 46 10 19 0 0 0 10 10 0 0 10 % G
% His: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 19 % H
% Ile: 0 10 0 10 0 10 0 0 0 0 0 19 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 10 10 10 0 0 19 0 0 % K
% Leu: 64 0 0 0 0 10 10 10 0 10 19 0 55 10 0 % L
% Met: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 10 10 10 % N
% Pro: 0 0 0 10 0 10 46 0 10 55 0 64 10 19 0 % P
% Gln: 0 0 0 0 0 46 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 64 10 55 10 10 0 0 19 0 10 0 0 0 0 % R
% Ser: 0 0 10 0 19 0 10 46 55 10 37 0 10 0 10 % S
% Thr: 0 0 55 0 10 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 10 0 0 0 0 10 10 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 10 10 0 0 10 0 0 0 0 0 0 55 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _