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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NODAL
All Species:
21.21
Human Site:
Y295
Identified Species:
46.67
UniProt:
Q96S42
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S42
NP_060525.3
347
39561
Y295
F
H
P
T
N
H
A
Y
I
Q
S
L
L
K
R
Chimpanzee
Pan troglodytes
XP_521502
347
39676
Y295
F
H
P
T
N
H
A
Y
I
Q
S
L
L
K
R
Rhesus Macaque
Macaca mulatta
XP_001108137
347
39778
Y295
F
H
P
T
N
H
A
Y
I
Q
S
L
L
K
R
Dog
Lupus familis
XP_546146
348
39415
Y296
F
H
P
T
N
H
A
Y
I
Q
S
L
L
K
R
Cat
Felis silvestris
Mouse
Mus musculus
P43021
354
40430
Y302
F
H
P
T
N
H
A
Y
I
Q
S
L
L
K
R
Rat
Rattus norvegicus
Q6HA10
452
50994
I399
L
E
P
T
N
H
A
I
I
Q
T
L
M
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90751
353
40328
I301
L
N
S
T
N
H
A
I
V
Q
T
L
V
N
S
Frog
Xenopus laevis
O13048
402
46253
Y350
V
K
P
N
N
H
A
Y
M
Q
S
L
L
N
Y
Zebra Danio
Brachydanio rerio
P85857
404
46271
I351
L
E
P
T
N
H
A
I
I
Q
T
L
M
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504709
365
41750
I312
L
N
A
T
N
H
A
I
I
Q
S
L
L
H
S
Sea Urchin
Strong. purpuratus
P48970
395
43818
I342
L
N
G
T
N
H
A
I
I
Q
T
L
V
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.5
85.3
N.A.
77.9
28.9
N.A.
N.A.
26
34
25
N.A.
N.A.
N.A.
24.6
26
Protein Similarity:
100
99.1
97.9
88.7
N.A.
83.3
42
N.A.
N.A.
43.6
49.7
42
N.A.
N.A.
N.A.
42.1
41
P-Site Identity:
100
100
100
100
N.A.
100
53.3
N.A.
N.A.
40
60
53.3
N.A.
N.A.
N.A.
60
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
66.6
N.A.
N.A.
66.6
66.6
66.6
N.A.
N.A.
N.A.
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
100
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
46
0
0
0
100
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
46
82
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
46
0
% K
% Leu:
46
0
0
0
0
0
0
0
0
0
0
100
64
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
19
0
0
% M
% Asn:
0
28
0
10
100
0
0
0
0
0
0
0
0
46
0
% N
% Pro:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
64
0
0
0
46
% S
% Thr:
0
0
0
91
0
0
0
0
0
0
37
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
10
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _