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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53RK
All Species:
37.27
Human Site:
S190
Identified Species:
74.55
UniProt:
Q96S44
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S44
NP_291028.3
253
28160
S190
D
F
G
L
S
F
I
S
A
L
P
E
D
K
G
Chimpanzee
Pan troglodytes
XP_514697
253
28128
S190
D
F
G
L
S
F
I
S
A
L
P
E
D
K
G
Rhesus Macaque
Macaca mulatta
XP_001107480
201
22218
G145
S
A
L
P
E
D
K
G
V
D
L
Y
V
L
E
Dog
Lupus familis
XP_853966
302
33650
S239
D
F
G
L
S
F
I
S
A
L
P
E
D
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99PW4
244
27375
S181
D
F
G
L
S
F
V
S
G
L
P
E
D
K
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425703
314
33606
S251
D
F
G
L
S
F
I
S
G
L
P
E
D
K
G
Frog
Xenopus laevis
NP_001089506
237
26742
S174
D
F
G
L
S
F
I
S
A
L
P
E
D
K
G
Zebra Danio
Brachydanio rerio
NP_001018386
231
26056
S168
D
F
G
L
S
Y
I
S
A
L
P
E
D
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647948
224
25346
N160
D
F
G
L
S
H
Y
N
Q
A
T
E
D
K
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300825
226
25241
S163
D
F
G
L
S
F
T
S
T
L
P
E
D
K
A
Maize
Zea mays
NP_001146448
226
25230
S163
D
F
G
L
S
F
T
S
T
I
P
E
D
K
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53323
261
29918
S189
D
F
G
L
G
S
V
S
N
L
V
E
D
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
68.3
78.4
N.A.
83.7
N.A.
N.A.
N.A.
56.3
66
61.2
N.A.
41.5
N.A.
N.A.
N.A.
Protein Similarity:
100
100
71.9
81.1
N.A.
88.9
N.A.
N.A.
N.A.
66.2
78.2
77.4
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
86.6
N.A.
N.A.
N.A.
93.3
100
93.3
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
93.3
N.A.
N.A.
N.A.
93.3
100
100
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
44.2
41.9
N.A.
N.A.
32.1
N.A.
Protein Similarity:
60.4
58.1
N.A.
N.A.
48.6
N.A.
P-Site Identity:
80
73.3
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
80
80
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
42
9
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
92
0
0
0
0
9
0
0
0
9
0
0
92
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
0
92
0
0
9
% E
% Phe:
0
92
0
0
0
67
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
92
0
9
0
0
9
17
0
0
0
0
0
75
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
92
0
% K
% Leu:
0
0
9
92
0
0
0
0
0
75
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
75
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
84
9
0
84
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
17
0
17
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
17
0
9
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _