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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGS
All Species:
9.09
Human Site:
S121
Identified Species:
18.18
UniProt:
Q96S52
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S52
NP_149975.1
555
61656
S121
H
E
E
E
A
L
S
S
G
S
V
Q
E
A
E
Chimpanzee
Pan troglodytes
XP_511797
555
61587
S121
H
E
E
E
A
L
S
S
G
S
V
Q
E
A
E
Rhesus Macaque
Macaca mulatta
XP_001107461
555
61735
S121
H
E
E
E
A
L
S
S
G
S
V
Q
E
A
E
Dog
Lupus familis
XP_548290
555
61611
L121
H
E
E
A
A
L
S
L
G
S
M
Q
E
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD26
555
61692
L121
H
E
E
E
A
L
S
L
G
S
V
H
E
A
E
Rat
Rattus norvegicus
Q5XI31
555
61706
L121
H
E
E
E
A
L
S
L
G
S
V
H
E
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507200
555
60959
L121
Q
E
E
V
A
L
G
L
A
N
V
Q
E
A
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087430
591
66086
Q149
E
E
E
A
L
G
L
Q
S
L
K
D
A
D
N
Zebra Danio
Brachydanio rerio
NP_001070082
566
62885
Q121
M
E
E
D
A
L
N
Q
P
T
A
A
E
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733060
536
60422
N127
L
E
K
L
L
L
E
N
H
V
Q
S
V
G
D
Honey Bee
Apis mellifera
XP_397105
540
60823
N113
I
I
Y
R
V
I
S
N
T
F
A
F
T
H
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781371
519
58212
R122
N
C
L
T
A
E
K
R
L
M
E
E
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.3
89.3
N.A.
91.8
91.3
N.A.
71.3
N.A.
55.1
53.5
N.A.
28.2
33.6
N.A.
35.3
Protein Similarity:
100
99.4
98.3
94.2
N.A.
95.6
95.3
N.A.
81.6
N.A.
70
69.4
N.A.
48.8
54.9
N.A.
49.3
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
53.3
N.A.
13.3
40
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
66.6
N.A.
13.3
66.6
N.A.
33.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
75
0
0
0
9
0
17
9
9
67
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
0
9
25
% D
% Glu:
9
84
75
42
0
9
9
0
0
0
9
9
67
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
9
9
0
50
0
0
0
0
9
0
% G
% His:
50
0
0
0
0
0
0
0
9
0
0
17
0
9
9
% H
% Ile:
9
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
0
0
0
9
0
0
0
0
% K
% Leu:
9
0
9
9
17
75
9
34
9
9
0
0
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
9
17
0
9
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
17
0
0
9
42
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
59
25
9
50
0
9
9
9
9
% S
% Thr:
0
0
0
9
0
0
0
0
9
9
0
0
9
0
0
% T
% Val:
0
0
0
9
9
0
0
0
0
9
50
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _