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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGS All Species: 26.67
Human Site: S152 Identified Species: 53.33
UniProt: Q96S52 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S52 NP_149975.1 555 61656 S152 Y V I S E H S S L L P Q D M M
Chimpanzee Pan troglodytes XP_511797 555 61587 S152 Y V I S E H S S L L P Q D M M
Rhesus Macaque Macaca mulatta XP_001107461 555 61735 S152 Y V I S E H S S L L P Q D M M
Dog Lupus familis XP_548290 555 61611 S152 Y V I S E H S S L L P Q D M M
Cat Felis silvestris
Mouse Mus musculus Q6PD26 555 61692 S152 Y V I S E H S S L L P Q D M M
Rat Rattus norvegicus Q5XI31 555 61706 S152 Y V I S E H S S L L P Q D M M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507200 555 60959 S152 Y V V P E A S S L L P Q D V M
Chicken Gallus gallus
Frog Xenopus laevis NP_001087430 591 66086 I179 F I L P E S S I L L P K G I S
Zebra Danio Brachydanio rerio NP_001070082 566 62885 V152 Y V I P E S S V L L P E D V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733060 536 60422 A155 L L T T E R S A L M R S D T P
Honey Bee Apis mellifera XP_397105 540 60823 N143 L L L F E T T N L N N A V L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781371 519 58212 V150 N P V G E I T V Y I F D H S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.3 89.3 N.A. 91.8 91.3 N.A. 71.3 N.A. 55.1 53.5 N.A. 28.2 33.6 N.A. 35.3
Protein Similarity: 100 99.4 98.3 94.2 N.A. 95.6 95.3 N.A. 81.6 N.A. 70 69.4 N.A. 48.8 54.9 N.A. 49.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 N.A. 33.3 60 N.A. 26.6 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 N.A. 66.6 73.3 N.A. 53.3 53.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 9 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 75 0 0 % D
% Glu: 0 0 0 0 100 0 0 0 0 0 0 9 0 0 0 % E
% Phe: 9 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 50 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 59 0 0 9 0 9 0 9 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % K
% Leu: 17 17 17 0 0 0 0 0 92 75 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 50 59 % M
% Asn: 9 0 0 0 0 0 0 9 0 9 9 0 0 0 0 % N
% Pro: 0 9 0 25 0 0 0 0 0 0 75 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 0 50 0 17 84 59 0 0 0 9 0 9 17 % S
% Thr: 0 0 9 9 0 9 17 0 0 0 0 0 0 9 0 % T
% Val: 0 67 17 0 0 0 0 17 0 0 0 0 9 17 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 67 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _