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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGS
All Species:
27.58
Human Site:
S214
Identified Species:
55.15
UniProt:
Q96S52
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S52
NP_149975.1
555
61656
S214
H
L
P
E
D
K
W
S
A
E
K
R
R
P
L
Chimpanzee
Pan troglodytes
XP_511797
555
61587
S214
H
L
P
E
D
K
W
S
A
E
K
R
R
P
L
Rhesus Macaque
Macaca mulatta
XP_001107461
555
61735
S214
H
L
P
E
D
K
W
S
A
E
K
R
R
P
L
Dog
Lupus familis
XP_548290
555
61611
S214
H
L
P
E
D
K
W
S
S
D
K
R
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD26
555
61692
S214
H
L
P
E
D
K
W
S
S
D
K
R
R
P
L
Rat
Rattus norvegicus
Q5XI31
555
61706
S214
H
L
P
E
D
K
W
S
S
D
K
R
R
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507200
555
60959
S214
R
L
S
G
D
K
W
S
S
D
R
R
R
P
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087430
591
66086
F250
G
K
F
S
K
E
D
F
E
N
S
R
R
A
F
Zebra Danio
Brachydanio rerio
NP_001070082
566
62885
M224
T
K
V
T
K
E
S
M
A
D
S
M
R
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733060
536
60422
S206
P
A
Y
D
V
I
V
S
V
L
N
P
K
P
R
Honey Bee
Apis mellifera
XP_397105
540
60823
D197
E
P
T
L
Y
S
L
D
E
K
N
R
R
R
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781371
519
58212
V198
A
L
I
R
T
V
I
V
P
E
A
S
L
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.3
89.3
N.A.
91.8
91.3
N.A.
71.3
N.A.
55.1
53.5
N.A.
28.2
33.6
N.A.
35.3
Protein Similarity:
100
99.4
98.3
94.2
N.A.
95.6
95.3
N.A.
81.6
N.A.
70
69.4
N.A.
48.8
54.9
N.A.
49.3
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
60
N.A.
13.3
13.3
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
N.A.
20
33.3
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
34
0
9
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
59
0
9
9
0
42
0
0
0
9
0
% D
% Glu:
9
0
0
50
0
17
0
0
17
34
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
17
% F
% Gly:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
9
0
0
0
0
0
0
0
9
% I
% Lys:
0
17
0
0
17
59
0
0
0
9
50
0
9
0
9
% K
% Leu:
0
67
0
9
0
0
9
0
0
9
0
0
9
0
59
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
17
0
0
0
0
% N
% Pro:
9
9
50
0
0
0
0
0
9
0
0
9
0
67
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
0
0
0
9
75
84
9
9
% R
% Ser:
0
0
9
9
0
9
9
67
34
0
17
9
0
0
0
% S
% Thr:
9
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
9
9
9
9
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
59
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _