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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGS All Species: 35.76
Human Site: S223 Identified Species: 71.52
UniProt: Q96S52 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S52 NP_149975.1 555 61656 S223 E K R R P L K S S L G Y E I T
Chimpanzee Pan troglodytes XP_511797 555 61587 S223 E K R R P L K S S L G Y E I T
Rhesus Macaque Macaca mulatta XP_001107461 555 61735 S223 E K R R P L K S S L G Y E I T
Dog Lupus familis XP_548290 555 61611 S223 D K R R P L K S S L G Y E I T
Cat Felis silvestris
Mouse Mus musculus Q6PD26 555 61692 S223 D K R R P L K S S L G Y E I T
Rat Rattus norvegicus Q5XI31 555 61706 S223 D K R R P L K S S L G Y E I T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507200 555 60959 S223 D R R R P L K S S L G Y E I T
Chicken Gallus gallus
Frog Xenopus laevis NP_001087430 591 66086 S259 N S R R A F K S S A G Y E I T
Zebra Danio Brachydanio rerio NP_001070082 566 62885 S233 D S M R A I K S S P G Y E I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733060 536 60422 T215 L N P K P R L T H A K W N I A
Honey Bee Apis mellifera XP_397105 540 60823 A206 K N R R R F P A S S A Y D I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781371 519 58212 Y207 E A S L D K H Y K T A R G V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.3 89.3 N.A. 91.8 91.3 N.A. 71.3 N.A. 55.1 53.5 N.A. 28.2 33.6 N.A. 35.3
Protein Similarity: 100 99.4 98.3 94.2 N.A. 95.6 95.3 N.A. 81.6 N.A. 70 69.4 N.A. 48.8 54.9 N.A. 49.3
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 86.6 N.A. 66.6 60 N.A. 13.3 33.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 N.A. 66.6 73.3 N.A. 33.3 53.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 17 0 0 9 0 17 17 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 42 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 34 0 0 0 0 0 0 0 0 0 0 0 75 0 0 % E
% Phe: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 75 0 9 0 0 % G
% His: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 0 92 0 % I
% Lys: 9 50 0 9 0 9 75 0 9 0 9 0 0 0 0 % K
% Leu: 9 0 0 9 0 59 9 0 0 59 0 0 0 0 9 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 17 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 9 0 67 0 9 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 75 84 9 9 0 0 0 0 0 9 0 0 0 % R
% Ser: 0 17 9 0 0 0 0 75 84 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 75 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 84 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _