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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGS
All Species:
36.06
Human Site:
S224
Identified Species:
72.12
UniProt:
Q96S52
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S52
NP_149975.1
555
61656
S224
K
R
R
P
L
K
S
S
L
G
Y
E
I
T
F
Chimpanzee
Pan troglodytes
XP_511797
555
61587
S224
K
R
R
P
L
K
S
S
L
G
Y
E
I
T
F
Rhesus Macaque
Macaca mulatta
XP_001107461
555
61735
S224
K
R
R
P
L
K
S
S
L
G
Y
E
I
T
F
Dog
Lupus familis
XP_548290
555
61611
S224
K
R
R
P
L
K
S
S
L
G
Y
E
I
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD26
555
61692
S224
K
R
R
P
L
K
S
S
L
G
Y
E
I
T
F
Rat
Rattus norvegicus
Q5XI31
555
61706
S224
K
R
R
P
L
K
S
S
L
G
Y
E
I
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507200
555
60959
S224
R
R
R
P
L
K
S
S
L
G
Y
E
I
T
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087430
591
66086
S260
S
R
R
A
F
K
S
S
A
G
Y
E
I
T
F
Zebra Danio
Brachydanio rerio
NP_001070082
566
62885
S234
S
M
R
A
I
K
S
S
P
G
Y
E
I
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733060
536
60422
H216
N
P
K
P
R
L
T
H
A
K
W
N
I
A
M
Honey Bee
Apis mellifera
XP_397105
540
60823
S207
N
R
R
R
F
P
A
S
S
A
Y
D
I
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781371
519
58212
K208
A
S
L
D
K
H
Y
K
T
A
R
G
V
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.3
89.3
N.A.
91.8
91.3
N.A.
71.3
N.A.
55.1
53.5
N.A.
28.2
33.6
N.A.
35.3
Protein Similarity:
100
99.4
98.3
94.2
N.A.
95.6
95.3
N.A.
81.6
N.A.
70
69.4
N.A.
48.8
54.9
N.A.
49.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
73.3
66.6
N.A.
13.3
33.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
73.3
73.3
N.A.
33.3
46.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
0
0
9
0
17
17
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
75
% F
% Gly:
0
0
0
0
0
0
0
0
0
75
0
9
0
0
0
% G
% His:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
92
0
9
% I
% Lys:
50
0
9
0
9
75
0
9
0
9
0
0
0
0
0
% K
% Leu:
0
0
9
0
59
9
0
0
59
0
0
0
0
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
9
0
67
0
9
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
75
84
9
9
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
17
9
0
0
0
0
75
84
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
9
0
0
0
0
75
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
84
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _