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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGS
All Species:
32.42
Human Site:
S431
Identified Species:
64.85
UniProt:
Q96S52
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S52
NP_149975.1
555
61656
S431
D
R
L
L
W
A
R
S
V
E
N
L
A
T
A
Chimpanzee
Pan troglodytes
XP_511797
555
61587
S431
D
R
L
L
W
A
R
S
V
E
N
L
A
T
A
Rhesus Macaque
Macaca mulatta
XP_001107461
555
61735
S431
D
R
L
L
W
A
R
S
V
E
N
L
A
T
A
Dog
Lupus familis
XP_548290
555
61611
S431
D
Q
L
L
W
A
R
S
V
E
N
L
A
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD26
555
61692
S431
D
R
L
L
W
A
R
S
V
E
N
L
A
T
A
Rat
Rattus norvegicus
Q5XI31
555
61706
S431
D
R
L
L
W
A
R
S
V
E
N
L
A
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507200
555
60959
T431
D
R
L
L
W
A
R
T
V
E
N
I
A
T
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087430
591
66086
V467
D
R
L
L
W
S
R
V
V
E
N
I
A
T
V
Zebra Danio
Brachydanio rerio
NP_001070082
566
62885
S441
D
R
L
M
W
S
R
S
V
E
N
I
A
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733060
536
60422
S413
Y
E
A
Y
L
R
R
S
A
I
R
H
I
S
T
Honey Bee
Apis mellifera
XP_397105
540
60823
G399
P
E
P
K
F
L
N
G
V
T
I
V
P
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781371
519
58212
Q393
V
M
P
V
F
L
A
Q
L
R
L
L
L
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.3
89.3
N.A.
91.8
91.3
N.A.
71.3
N.A.
55.1
53.5
N.A.
28.2
33.6
N.A.
35.3
Protein Similarity:
100
99.4
98.3
94.2
N.A.
95.6
95.3
N.A.
81.6
N.A.
70
69.4
N.A.
48.8
54.9
N.A.
49.3
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
80
N.A.
73.3
80
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
86.6
100
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
59
9
0
9
0
0
0
75
0
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
17
0
0
0
0
0
0
0
75
0
0
0
0
0
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
9
25
9
0
9
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
75
67
9
17
0
0
9
0
9
59
9
9
0
% L
% Met:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
75
0
0
0
0
% N
% Pro:
9
0
17
0
0
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
67
0
0
0
9
84
0
0
9
9
0
0
0
0
% R
% Ser:
0
0
0
0
0
17
0
67
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
9
0
0
0
75
9
% T
% Val:
9
0
0
9
0
0
0
9
84
0
0
9
0
0
17
% V
% Trp:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _