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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGS All Species: 23.94
Human Site: S547 Identified Species: 47.88
UniProt: Q96S52 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S52 NP_149975.1 555 61656 S547 I F L E T R K S W R K P E K T
Chimpanzee Pan troglodytes XP_511797 555 61587 S547 I F L E T H K S W R K P E K T
Rhesus Macaque Macaca mulatta XP_001107461 555 61735 S547 I F L E T H K S W K K P E K T
Dog Lupus familis XP_548290 555 61611 S547 I F L E T R K S W K K P E K I
Cat Felis silvestris
Mouse Mus musculus Q6PD26 555 61692 S547 I F Q E T R K S W K K P E K I
Rat Rattus norvegicus Q5XI31 555 61706 S547 I F L E T H K S W K K P E K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507200 555 60959 A547 I L R E A R Q A R K E S L K T
Chicken Gallus gallus
Frog Xenopus laevis NP_001087430 591 66086 S583 I A K E Y K Q S K K E P M K T
Zebra Danio Brachydanio rerio NP_001070082 566 62885 R557 I V S E V K K R R A E K Q A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733060 536 60422 A529 M L R G V L Q A R R K E K Q S
Honey Bee Apis mellifera XP_397105 540 60823 T515 D Q K Y A V Y T P L F L P T M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781371 519 58212 L509 A F F D P S L L Q L L Y F P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.3 89.3 N.A. 91.8 91.3 N.A. 71.3 N.A. 55.1 53.5 N.A. 28.2 33.6 N.A. 35.3
Protein Similarity: 100 99.4 98.3 94.2 N.A. 95.6 95.3 N.A. 81.6 N.A. 70 69.4 N.A. 48.8 54.9 N.A. 49.3
P-Site Identity: 100 93.3 86.6 86.6 N.A. 80 80 N.A. 33.3 N.A. 40 20 N.A. 13.3 0 N.A. 6.6
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 86.6 86.6 N.A. 60 N.A. 66.6 40 N.A. 53.3 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 17 0 0 17 0 9 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 75 0 0 0 0 0 0 25 9 50 0 0 % E
% Phe: 0 59 9 0 0 0 0 0 0 0 9 0 9 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % H
% Ile: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % I
% Lys: 0 0 17 0 0 17 59 0 9 50 59 9 9 67 9 % K
% Leu: 0 17 42 0 0 9 9 9 0 17 9 9 9 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 0 0 9 0 0 59 9 9 0 % P
% Gln: 0 9 9 0 0 0 25 0 9 0 0 0 9 9 0 % Q
% Arg: 0 0 17 0 0 34 0 9 25 25 0 0 0 0 0 % R
% Ser: 0 0 9 0 0 9 0 59 0 0 0 9 0 0 9 % S
% Thr: 0 0 0 0 50 0 0 9 0 0 0 0 0 9 42 % T
% Val: 0 9 0 0 17 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 9 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _