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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGS
All Species:
3.94
Human Site:
Y244
Identified Species:
7.88
UniProt:
Q96S52
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S52
NP_149975.1
555
61656
Y244
D
P
K
S
H
D
V
Y
W
D
I
E
G
A
V
Chimpanzee
Pan troglodytes
XP_511797
555
61587
H244
D
P
K
S
H
D
V
H
W
D
I
E
G
A
V
Rhesus Macaque
Macaca mulatta
XP_001107461
555
61735
H244
D
P
K
S
H
D
V
H
W
D
I
E
G
A
V
Dog
Lupus familis
XP_548290
555
61611
H244
D
P
K
S
H
D
V
H
W
D
I
E
G
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD26
555
61692
H244
D
P
K
S
H
D
V
H
W
D
I
E
G
A
V
Rat
Rattus norvegicus
Q5XI31
555
61706
H244
D
P
K
S
H
D
V
H
W
D
I
E
E
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507200
555
60959
R244
D
P
R
S
H
D
V
R
W
A
I
E
G
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087430
591
66086
S280
D
P
K
S
H
D
L
S
W
N
I
S
S
A
S
Zebra Danio
Brachydanio rerio
NP_001070082
566
62885
H254
D
P
K
S
H
S
L
H
W
D
I
E
G
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733060
536
60422
V236
I
E
P
W
L
A
K
V
S
G
V
S
N
Y
T
Honey Bee
Apis mellifera
XP_397105
540
60823
D227
D
P
E
K
L
K
I
D
W
N
L
R
E
M
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781371
519
58212
Y228
E
S
M
R
S
F
R
Y
T
P
G
Y
E
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.3
89.3
N.A.
91.8
91.3
N.A.
71.3
N.A.
55.1
53.5
N.A.
28.2
33.6
N.A.
35.3
Protein Similarity:
100
99.4
98.3
94.2
N.A.
95.6
95.3
N.A.
81.6
N.A.
70
69.4
N.A.
48.8
54.9
N.A.
49.3
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
80
N.A.
80
N.A.
60
73.3
N.A.
0
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
86.6
N.A.
73.3
93.3
N.A.
6.6
53.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
9
0
0
0
67
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
84
0
0
0
0
67
0
9
0
59
0
0
0
0
0
% D
% Glu:
9
9
9
0
0
0
0
0
0
0
0
67
25
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
9
0
59
9
0
% G
% His:
0
0
0
0
75
0
0
50
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
9
0
0
0
75
0
0
0
0
% I
% Lys:
0
0
67
9
0
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
17
0
17
0
0
0
9
0
0
9
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% N
% Pro:
0
84
9
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
9
0
0
9
9
0
0
0
9
0
0
0
% R
% Ser:
0
9
0
75
9
9
0
9
9
0
0
17
9
0
17
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
59
9
0
0
9
0
0
0
67
% V
% Trp:
0
0
0
9
0
0
0
0
84
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _