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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRNIP1
All Species:
20.3
Human Site:
S254
Identified Species:
31.9
UniProt:
Q96S55
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S55
NP_064520.2
665
72133
S254
G
Q
D
T
L
L
R
S
L
L
E
T
N
E
I
Chimpanzee
Pan troglodytes
XP_001159632
665
72086
S254
G
Q
D
T
L
L
R
S
L
L
E
T
N
E
I
Rhesus Macaque
Macaca mulatta
XP_001090684
665
72184
S254
G
Q
D
T
L
L
R
S
L
L
E
T
N
E
I
Dog
Lupus familis
XP_535865
427
47458
P49
P
S
L
I
L
W
G
P
P
G
C
G
K
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91XU0
660
71775
S249
G
Q
E
T
L
L
R
S
L
L
E
A
N
E
I
Rat
Rattus norvegicus
Q8CG07
660
71915
S249
G
Q
E
T
L
L
R
S
L
L
E
T
N
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510043
468
51745
H90
G
S
E
T
T
L
A
H
I
I
A
N
N
C
K
Chicken
Gallus gallus
XP_418979
562
61303
K184
I
A
N
S
S
K
K
K
G
M
R
F
V
T
L
Frog
Xenopus laevis
NP_001089187
572
62408
G194
I
I
L
W
G
P
P
G
C
G
K
T
T
L
A
Zebra Danio
Brachydanio rerio
NP_998085
546
59562
A168
G
C
G
K
T
T
L
A
H
I
I
A
S
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392908
494
55235
C116
I
L
W
G
P
P
G
C
G
K
T
S
L
A
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795793
672
73552
T250
K
T
N
A
Q
S
P
T
P
Q
S
T
K
P
T
Poplar Tree
Populus trichocarpa
XP_002316599
553
59887
K175
W
G
P
P
G
T
G
K
T
S
I
A
R
A
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173839
525
57378
G147
I
V
F
W
G
P
P
G
T
G
K
T
S
I
A
Baker's Yeast
Sacchar. cerevisiae
P40151
587
66526
S205
S
N
E
S
N
V
G
S
R
Y
F
M
I
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
63.1
N.A.
95.3
95
N.A.
53.6
63.6
56.6
56.2
N.A.
N.A.
39.2
N.A.
38.2
Protein Similarity:
100
99.5
99.8
63.9
N.A.
97.2
96.8
N.A.
60.7
71.8
68.4
65.7
N.A.
N.A.
52.7
N.A.
55.2
P-Site Identity:
100
100
100
6.6
N.A.
86.6
93.3
N.A.
26.6
0
6.6
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
100
N.A.
46.6
33.3
13.3
33.3
N.A.
N.A.
6.6
N.A.
20
Percent
Protein Identity:
39.7
N.A.
N.A.
39.7
35.4
N.A.
Protein Similarity:
51.1
N.A.
N.A.
52.7
50.2
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
7
7
0
0
7
20
0
14
14
% A
% Cys:
0
7
0
0
0
0
0
7
7
0
7
0
0
7
0
% C
% Asp:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
27
0
0
0
0
0
0
0
34
0
0
40
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
7
7
0
0
0
% F
% Gly:
47
7
7
7
20
0
27
14
14
20
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
27
7
0
7
0
0
0
0
7
14
14
0
7
7
47
% I
% Lys:
7
0
0
7
0
7
7
14
0
7
14
0
14
0
7
% K
% Leu:
0
7
14
0
40
40
7
0
34
34
0
0
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
0
7
14
0
7
0
0
0
0
0
0
7
40
0
7
% N
% Pro:
7
0
7
7
7
20
20
7
14
0
0
0
0
7
0
% P
% Gln:
0
34
0
0
7
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
34
0
7
0
7
0
7
0
0
% R
% Ser:
7
14
0
14
7
7
0
40
0
7
7
7
14
7
0
% S
% Thr:
0
7
0
40
14
14
0
7
14
0
7
47
7
14
20
% T
% Val:
0
7
0
0
0
7
0
0
0
0
0
0
7
0
0
% V
% Trp:
7
0
7
14
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _