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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRNIP1
All Species:
20.91
Human Site:
S457
Identified Species:
32.86
UniProt:
Q96S55
Number Species:
14
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S55
NP_064520.2
665
72133
S457
A
V
L
A
R
L
S
S
R
K
M
F
C
K
K
Chimpanzee
Pan troglodytes
XP_001159632
665
72086
S457
A
V
L
A
R
L
S
S
R
K
M
F
C
K
K
Rhesus Macaque
Macaca mulatta
XP_001090684
665
72184
S457
A
V
L
A
R
L
S
S
R
K
M
F
C
K
K
Dog
Lupus familis
XP_535865
427
47458
E245
I
T
E
N
D
V
K
E
G
L
Q
R
S
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91XU0
660
71775
S452
A
V
L
A
R
L
S
S
R
K
V
F
C
K
K
Rat
Rattus norvegicus
Q8CG07
660
71915
S452
A
V
L
A
R
L
S
S
R
K
M
F
C
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510043
468
51745
E286
I
T
E
S
D
V
K
E
G
L
Q
R
S
H
I
Chicken
Gallus gallus
XP_418979
562
61303
E380
I
T
E
E
H
V
K
E
G
L
Q
R
S
H
I
Frog
Xenopus laevis
NP_001089187
572
62408
E390
K
Q
G
I
V
I
K
E
E
H
I
K
E
G
L
Zebra Danio
Brachydanio rerio
NP_998085
546
59562
L364
E
Q
H
I
K
E
A
L
Q
R
S
H
I
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392908
494
55235
D312
G
P
V
T
I
T
L
D
D
I
K
E
S
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795793
672
73552
T459
L
H
K
T
C
W
S
T
T
I
S
I
E
R
E
Poplar Tree
Populus trichocarpa
XP_002316599
553
59887
S371
D
A
K
E
A
L
Q
S
K
H
L
A
Y
D
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173839
525
57378
G343
H
L
A
Y
D
K
A
G
E
Q
H
Y
N
L
I
Baker's Yeast
Sacchar. cerevisiae
P40151
587
66526
F404
H
Y
D
T
I
S
A
F
H
K
S
I
R
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
63.1
N.A.
95.3
95
N.A.
53.6
63.6
56.6
56.2
N.A.
N.A.
39.2
N.A.
38.2
Protein Similarity:
100
99.5
99.8
63.9
N.A.
97.2
96.8
N.A.
60.7
71.8
68.4
65.7
N.A.
N.A.
52.7
N.A.
55.2
P-Site Identity:
100
100
100
0
N.A.
93.3
100
N.A.
0
0
0
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
13.3
6.6
13.3
26.6
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
39.7
N.A.
N.A.
39.7
35.4
N.A.
Protein Similarity:
51.1
N.A.
N.A.
52.7
50.2
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
7
7
34
7
0
20
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
34
0
0
% C
% Asp:
7
0
7
0
20
0
0
7
7
0
0
0
0
7
0
% D
% Glu:
7
0
20
14
0
7
0
27
14
0
0
7
14
0
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
34
0
0
0
% F
% Gly:
7
0
7
0
0
0
0
7
20
0
0
0
0
14
7
% G
% His:
14
7
7
0
7
0
0
0
7
14
7
7
0
20
0
% H
% Ile:
20
0
0
14
14
7
0
0
0
14
7
14
7
0
27
% I
% Lys:
7
0
14
0
7
7
27
0
7
40
7
7
0
34
40
% K
% Leu:
7
7
34
0
0
40
7
7
0
20
7
0
0
20
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
27
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
14
0
0
0
0
7
0
7
7
20
0
0
0
0
% Q
% Arg:
0
0
0
0
34
0
0
0
34
7
0
20
7
7
7
% R
% Ser:
0
0
0
7
0
7
40
40
0
0
20
0
27
0
0
% S
% Thr:
0
20
0
20
0
7
0
7
7
0
0
0
0
0
0
% T
% Val:
0
34
7
0
7
20
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
0
0
0
0
0
7
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _