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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WRNIP1 All Species: 23.03
Human Site: S590 Identified Species: 36.19
UniProt: Q96S55 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S55 NP_064520.2 665 72133 S590 Y F A R A P K S I E V Y S A Y
Chimpanzee Pan troglodytes XP_001159632 665 72086 S590 Y F A R A P K S I E V Y S A Y
Rhesus Macaque Macaca mulatta XP_001090684 665 72184 S590 Y F A R A P K S I E V Y S A Y
Dog Lupus familis XP_535865 427 47458 P372 C L R N H Q G P L P P V P L H
Cat Felis silvestris
Mouse Mus musculus Q91XU0 660 71775 S585 Y F A R A P K S I E V Y S A Y
Rat Rattus norvegicus Q8CG07 660 71915 S585 Y F A R A P K S I E V Y S A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510043 468 51745 P413 C L R N H Q G P L P P V P L H
Chicken Gallus gallus XP_418979 562 61303 P507 C L R M H T G P L P P V P L H
Frog Xenopus laevis NP_001089187 572 62408 K517 N K V K N C L K N H K G P L P
Zebra Danio Brachydanio rerio NP_998085 546 59562 P491 R N H K G P L P S V P L H L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392908 494 55235 E439 A A Q R V I A E H K G P Q P G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795793 672 73552 S599 Y L S R A P K S R Q V A T V Y
Poplar Tree Populus trichocarpa XP_002316599 553 59887 V498 S V G Q N E G V P L H L R N A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173839 525 57378 T470 L H L R N A P T K L M K E L G
Baker's Yeast Sacchar. cerevisiae P40151 587 66526 Y531 K L M E E L G Y H K G Y K Y N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 63.1 N.A. 95.3 95 N.A. 53.6 63.6 56.6 56.2 N.A. N.A. 39.2 N.A. 38.2
Protein Similarity: 100 99.5 99.8 63.9 N.A. 97.2 96.8 N.A. 60.7 71.8 68.4 65.7 N.A. N.A. 52.7 N.A. 55.2
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 0 0 0 6.6 N.A. N.A. 6.6 N.A. 53.3
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 13.3 13.3 6.6 13.3 N.A. N.A. 13.3 N.A. 73.3
Percent
Protein Identity: 39.7 N.A. N.A. 39.7 35.4 N.A.
Protein Similarity: 51.1 N.A. N.A. 52.7 50.2 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 6.6 N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 34 0 40 7 7 0 0 0 0 7 0 34 7 % A
% Cys: 20 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 7 7 0 7 0 34 0 0 7 0 0 % E
% Phe: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 7 0 34 0 0 0 14 7 0 0 14 % G
% His: 0 7 7 0 20 0 0 0 14 7 7 0 7 0 20 % H
% Ile: 0 0 0 0 0 7 0 0 34 0 0 0 0 0 0 % I
% Lys: 7 7 0 14 0 0 40 7 7 14 7 7 7 0 0 % K
% Leu: 7 34 7 0 0 7 14 0 20 14 0 14 0 40 0 % L
% Met: 0 0 7 7 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 7 7 0 14 20 0 0 0 7 0 0 0 0 7 7 % N
% Pro: 0 0 0 0 0 47 7 27 7 20 27 7 27 7 7 % P
% Gln: 0 0 7 7 0 14 0 0 0 7 0 0 7 0 0 % Q
% Arg: 7 0 20 54 0 0 0 0 7 0 0 0 7 0 7 % R
% Ser: 7 0 7 0 0 0 0 40 7 0 0 0 34 0 0 % S
% Thr: 0 0 0 0 0 7 0 7 0 0 0 0 7 0 0 % T
% Val: 0 7 7 0 7 0 0 7 0 7 40 20 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 40 0 0 0 0 0 0 7 0 0 0 40 0 7 40 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _