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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WRNIP1 All Species: 19.39
Human Site: Y434 Identified Species: 30.48
UniProt: Q96S55 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S55 NP_064520.2 665 72133 Y434 K A V D T L A Y L S D G D A R
Chimpanzee Pan troglodytes XP_001159632 665 72086 Y434 K A V D T L A Y L S D G D A R
Rhesus Macaque Macaca mulatta XP_001090684 665 72184 Y434 K A V D T L A Y L S D G D A R
Dog Lupus familis XP_535865 427 47458 L227 A R A G L N G L Q L A V L A S
Cat Felis silvestris
Mouse Mus musculus Q91XU0 660 71775 Y429 K A V D T L A Y L S D G D A R
Rat Rattus norvegicus Q8CG07 660 71915 Y429 K A V D T L A Y L S D G D A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510043 468 51745 A268 Q A R L T P G A T K P S D S P
Chicken Gallus gallus XP_418979 562 61303 F362 G K T T L L S F T E G C S V N
Frog Xenopus laevis NP_001089187 572 62408 Q372 N G L Q L S V Q A S L A A E K
Zebra Danio Brachydanio rerio NP_998085 546 59562 S346 A C V L Q S S S N H N R S S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392908 494 55235 K294 L E L A V Q C K L P N N E D F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795793 672 73552 L433 L S P E S I M L I L E R A L K
Poplar Tree Populus trichocarpa XP_002316599 553 59887 G353 A A R V G S D G D L R L A S V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173839 525 57378 I325 G T D A V V S I D D A K E A L
Baker's Yeast Sacchar. cerevisiae P40151 587 66526 G385 I K N N S S N G L N T Y Y D P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 63.1 N.A. 95.3 95 N.A. 53.6 63.6 56.6 56.2 N.A. N.A. 39.2 N.A. 38.2
Protein Similarity: 100 99.5 99.8 63.9 N.A. 97.2 96.8 N.A. 60.7 71.8 68.4 65.7 N.A. N.A. 52.7 N.A. 55.2
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 20 6.6 6.6 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 33.3 20 20 26.6 N.A. N.A. 26.6 N.A. 46.6
Percent
Protein Identity: 39.7 N.A. N.A. 39.7 35.4 N.A.
Protein Similarity: 51.1 N.A. N.A. 52.7 50.2 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 47 7 14 0 0 34 7 7 0 14 7 20 47 0 % A
% Cys: 0 7 0 0 0 0 7 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 7 34 0 0 7 0 14 7 34 0 40 14 0 % D
% Glu: 0 7 0 7 0 0 0 0 0 7 7 0 14 7 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % F
% Gly: 14 7 0 7 7 0 14 14 0 0 7 34 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 7 0 7 7 0 0 0 0 0 0 % I
% Lys: 34 14 0 0 0 0 0 7 0 7 0 7 0 0 14 % K
% Leu: 14 0 14 14 20 40 0 14 47 20 7 7 7 7 7 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 7 0 7 7 0 7 7 14 7 0 0 7 % N
% Pro: 0 0 7 0 0 7 0 0 0 7 7 0 0 0 14 % P
% Gln: 7 0 0 7 7 7 0 7 7 0 0 0 0 0 0 % Q
% Arg: 0 7 14 0 0 0 0 0 0 0 7 14 0 0 34 % R
% Ser: 0 7 0 0 14 27 20 7 0 40 0 7 14 20 7 % S
% Thr: 0 7 7 7 40 0 0 0 14 0 7 0 0 0 7 % T
% Val: 0 0 40 7 14 7 7 0 0 0 0 7 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 34 0 0 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _