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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WRNIP1 All Species: 18.18
Human Site: Y500 Identified Species: 28.57
UniProt: Q96S55 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S55 NP_064520.2 665 72133 Y500 D R A G E E H Y N C I S A L H
Chimpanzee Pan troglodytes XP_001159632 665 72086 Y500 D R A G E E H Y N C I S A L H
Rhesus Macaque Macaca mulatta XP_001090684 665 72184 Y500 D R A G E E H Y N C I S A L H
Dog Lupus familis XP_535865 427 47458 L288 L Y W L A R M L E G G E D P L
Cat Felis silvestris
Mouse Mus musculus Q91XU0 660 71775 Y495 D R A G E E H Y N C I S A L H
Rat Rattus norvegicus Q8CG07 660 71915 Y495 D R A G E E H Y N C I S A L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510043 468 51745 L329 L Y W L A R M L E G G E D P L
Chicken Gallus gallus XP_418979 562 61303 L423 L Y W L A R M L E G G E D P L
Frog Xenopus laevis NP_001089187 572 62408 W433 D K N A S L Y W L G R M L E G
Zebra Danio Brachydanio rerio NP_998085 546 59562 G407 W L A R M L E G G E D P L Y V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392908 494 55235 L355 E N A S L Y W L T R M I L G G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795793 672 73552 A502 G S T G G Q Q A D A S K V L R
Poplar Tree Populus trichocarpa XP_002316599 553 59887 E414 V R M L E G G E Q P L Y I A R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173839 525 57378 L386 P L Y I A R R L I R F A S E D
Baker's Yeast Sacchar. cerevisiae P40151 587 66526 L447 I A S E D I G L R D S S L L P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 63.1 N.A. 95.3 95 N.A. 53.6 63.6 56.6 56.2 N.A. N.A. 39.2 N.A. 38.2
Protein Similarity: 100 99.5 99.8 63.9 N.A. 97.2 96.8 N.A. 60.7 71.8 68.4 65.7 N.A. N.A. 52.7 N.A. 55.2
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 0 0 6.6 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 0 N.A. 100 100 N.A. 0 0 26.6 6.6 N.A. N.A. 20 N.A. 26.6
Percent
Protein Identity: 39.7 N.A. N.A. 39.7 35.4 N.A.
Protein Similarity: 51.1 N.A. N.A. 52.7 50.2 N.A.
P-Site Identity: 13.3 N.A. N.A. 0 13.3 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 47 7 27 0 0 7 0 7 0 7 34 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 34 0 0 0 0 0 % C
% Asp: 40 0 0 0 7 0 0 0 7 7 7 0 20 0 7 % D
% Glu: 7 0 0 7 40 34 7 7 20 7 0 20 0 14 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 7 0 0 40 7 7 14 7 7 27 20 0 0 7 14 % G
% His: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 34 % H
% Ile: 7 0 0 7 0 7 0 0 7 0 34 7 7 0 0 % I
% Lys: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 20 14 0 27 7 14 0 40 7 0 7 0 27 47 20 % L
% Met: 0 0 7 0 7 0 20 0 0 0 7 7 0 0 0 % M
% Asn: 0 7 7 0 0 0 0 0 34 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 0 0 0 0 0 7 0 7 0 20 7 % P
% Gln: 0 0 0 0 0 7 7 0 7 0 0 0 0 0 0 % Q
% Arg: 0 40 0 7 0 27 7 0 7 14 7 0 0 0 14 % R
% Ser: 0 7 7 7 7 0 0 0 0 0 14 40 7 0 0 % S
% Thr: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % V
% Trp: 7 0 20 0 0 0 7 7 0 0 0 0 0 0 0 % W
% Tyr: 0 20 7 0 0 7 7 34 0 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _