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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WRNIP1 All Species: 18.18
Human Site: Y534 Identified Species: 28.57
UniProt: Q96S55 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S55 NP_064520.2 665 72133 Y534 E G G E D P L Y V A R R L V R
Chimpanzee Pan troglodytes XP_001159632 665 72086 Y534 E G G E D P L Y V A R R L V R
Rhesus Macaque Macaca mulatta XP_001090684 665 72184 Y534 E G G E D P L Y V A R R L V R
Dog Lupus familis XP_535865 427 47458 A322 S A L T Q A V A A Y Q G C H F
Cat Felis silvestris
Mouse Mus musculus Q91XU0 660 71775 Y529 E G G E D P L Y V A R R L V R
Rat Rattus norvegicus Q8CG07 660 71915 Y529 E G G E D P L Y V A R R L V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510043 468 51745 A363 L A L P Q A V A A Y Q G C H F
Chicken Gallus gallus XP_418979 562 61303 A457 L A L T Q A V A A Y Q G C H F
Frog Xenopus laevis NP_001089187 572 62408 L467 G L A D P Q A L T Q A V S T Y
Zebra Danio Brachydanio rerio NP_998085 546 59562 F441 L S Q A V A A F Q A C H L I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392908 494 55235 E389 L E D P K A L E I A I N T M H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795793 672 73552 H536 Y D K S G E E H Y N C A S A L
Poplar Tree Populus trichocarpa XP_002316599 553 59887 A448 Q A V A C Y Q A C H F L G M P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173839 525 57378 C420 H F L G M P E C N V I L A Q C
Baker's Yeast Sacchar. cerevisiae P40151 587 66526 A481 A L A Q C C V A L A R A P K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 63.1 N.A. 95.3 95 N.A. 53.6 63.6 56.6 56.2 N.A. N.A. 39.2 N.A. 38.2
Protein Similarity: 100 99.5 99.8 63.9 N.A. 97.2 96.8 N.A. 60.7 71.8 68.4 65.7 N.A. N.A. 52.7 N.A. 55.2
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 0 0 0 13.3 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 13.3 13.3 6.6 26.6 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: 39.7 N.A. N.A. 39.7 35.4 N.A.
Protein Similarity: 51.1 N.A. N.A. 52.7 50.2 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 13.3 N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 27 14 14 0 34 14 34 20 54 7 14 7 7 0 % A
% Cys: 0 0 0 0 14 7 0 7 7 0 14 0 20 0 7 % C
% Asp: 0 7 7 7 34 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 34 7 0 34 0 7 14 7 0 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 7 0 0 7 0 0 0 20 % F
% Gly: 7 34 34 7 7 0 0 0 0 0 0 20 7 0 7 % G
% His: 7 0 0 0 0 0 0 7 0 7 0 7 0 20 7 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 14 0 0 7 0 % I
% Lys: 0 0 7 0 7 0 0 0 0 0 0 0 0 7 0 % K
% Leu: 27 14 27 0 0 0 40 7 7 0 0 14 40 0 7 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 14 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 7 0 7 0 0 0 % N
% Pro: 0 0 0 14 7 40 0 0 0 0 0 0 7 0 7 % P
% Gln: 7 0 7 7 20 7 7 0 7 7 20 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 40 34 0 0 34 % R
% Ser: 7 7 0 7 0 0 0 0 0 0 0 0 14 0 7 % S
% Thr: 0 0 0 14 0 0 0 0 7 0 0 0 7 7 0 % T
% Val: 0 0 7 0 7 0 27 0 34 7 0 7 0 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 34 7 20 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _