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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WRNIP1 All Species: 19.09
Human Site: Y594 Identified Species: 30
UniProt: Q96S55 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S55 NP_064520.2 665 72133 Y594 A P K S I E V Y S A Y N N V K
Chimpanzee Pan troglodytes XP_001159632 665 72086 Y594 A P K S I E V Y S A Y N N V K
Rhesus Macaque Macaca mulatta XP_001090684 665 72184 Y594 A P K S I E V Y S A Y N N V K
Dog Lupus familis XP_535865 427 47458 V376 H Q G P L P P V P L H L R N A
Cat Felis silvestris
Mouse Mus musculus Q91XU0 660 71775 Y589 A P K S I E V Y S A Y N N V K
Rat Rattus norvegicus Q8CG07 660 71915 Y589 A P K S I E V Y S A Y N N V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510043 468 51745 V417 H Q G P L P P V P L H L R N A
Chicken Gallus gallus XP_418979 562 61303 V511 H T G P L P P V P L H L R N A
Frog Xenopus laevis NP_001089187 572 62408 G521 N C L K N H K G P L P P V P L
Zebra Danio Brachydanio rerio NP_998085 546 59562 L495 G P L P S V P L H L R N A P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392908 494 55235 P443 V I A E H K G P Q P G V P L H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795793 672 73552 A603 A P K S R Q V A T V Y A R V K
Poplar Tree Populus trichocarpa XP_002316599 553 59887 L502 N E G V P L H L R N A P T K L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173839 525 57378 K474 N A P T K L M K E L G Y G K E
Baker's Yeast Sacchar. cerevisiae P40151 587 66526 Y535 E L G Y H K G Y K Y N P D Y I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 63.1 N.A. 95.3 95 N.A. 53.6 63.6 56.6 56.2 N.A. N.A. 39.2 N.A. 38.2
Protein Similarity: 100 99.5 99.8 63.9 N.A. 97.2 96.8 N.A. 60.7 71.8 68.4 65.7 N.A. N.A. 52.7 N.A. 55.2
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 0 0 0 13.3 N.A. N.A. 0 N.A. 53.3
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 13.3 13.3 0 13.3 N.A. N.A. 13.3 N.A. 66.6
Percent
Protein Identity: 39.7 N.A. N.A. 39.7 35.4 N.A.
Protein Similarity: 51.1 N.A. N.A. 52.7 50.2 N.A.
P-Site Identity: 0 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 0 N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 7 7 0 0 0 0 7 0 34 7 7 7 0 20 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % D
% Glu: 7 7 0 7 0 34 0 0 7 0 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 34 0 0 0 14 7 0 0 14 0 7 0 0 % G
% His: 20 0 0 0 14 7 7 0 7 0 20 0 0 0 7 % H
% Ile: 0 7 0 0 34 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 0 40 7 7 14 7 7 7 0 0 0 0 14 40 % K
% Leu: 0 7 14 0 20 14 0 14 0 40 0 20 0 7 14 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 20 0 0 0 7 0 0 0 0 7 7 40 34 20 0 % N
% Pro: 0 47 7 27 7 20 27 7 27 7 7 20 7 14 0 % P
% Gln: 0 14 0 0 0 7 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 0 7 0 7 0 27 0 0 % R
% Ser: 0 0 0 40 7 0 0 0 34 0 0 0 0 0 0 % S
% Thr: 0 7 0 7 0 0 0 0 7 0 0 0 7 0 7 % T
% Val: 7 0 0 7 0 7 40 20 0 7 0 7 7 40 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 40 0 7 40 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _